Abstract: Compositions of and methods for making and using alpha-1 antitrypsin (AAT) fusion molecules or peptide derivatives thereof are disclosed. The compositions and methods relate to generating an AAT fusion molecule of use in pharmaceutically acceptable compositions to treat a subject in need of AAT therapy or treatment. Compositions and methods disclosed herein concern linking AAT or derivative thereof to an immune fragment.
Type:
Application
Filed:
January 10, 2013
Publication date:
November 27, 2014
Applicants:
KONKUK UNIVERSITY, OMNI BIO PHARMACEUTICAL, INC., THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
Inventors:
Soohyun Kim, Charles A. Dinarello, James D. Crapo
Abstract: Embodiments herein report methods and compositions for treating or preventing adverse effects of radiation therapies. In certain embodiments, compositions and methods relate to reducing or inhibiting damage due to acute, periodic or chronic radiation exposure.
Type:
Application
Filed:
March 9, 2012
Publication date:
April 17, 2014
Applicant:
OMNI BIO PHARMACEUTICAL, INC.
Inventors:
James D. Crapo, A. Mario Q. Marcondes, H. Joachim Deeg