Abstract: The system for management of racks and tubes position for clinical chemistry laboratories of the invention comprises tubes (10) capable of containing human biological material, a rack (20) configured for receiving and/or holding the tubes (10) to be stocked, a supporting base (30) configured for supporting the rack (20) thereon, reading means (50) configured for reading an identificator (RID) of the rack (20) to be put onto the supporting base (30) and an identificator (TID) of the tube to be put into the rack (20), a camera (40) for detecting the rack (20) on the supporting base (30), and at least one of the tubes (10) into the rack (20), a processing unit (60) for mapping the detected rack (20) into a plurality of allowed positions (Pi) and the detected tube (10) into a tube position (P) comprised in said plurality of allowed positions (Pi).