Patents Assigned to ON TARGET LABORATORIES, INC.
  • CA IX-NIR dyes and their uses
    Patent number: 11555821
    Abstract: The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: January 17, 2023
    Assignee: ON TARGET LABORATORIES, INC.
    Inventors: Sumith A. Kularatne, Mini Thomas