Patents Assigned to Onclave Therapeutics
  • Detection of amyloid deposits using anti-amyloid antibodies
    Patent number: 8636981
    Abstract: Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: January 28, 2014
    Assignee: Onclave Therapeutics
    Inventors: Dale B. Schenk, Peter A. Seubert, Jonathan Wall
  • ANTIBODY FORMULATIONS AND METHODS
    Publication number: 20130295082
    Abstract: Antibody formulations and methods useful for prophylaxis or treatment of amyloidosis, including AA amyloidosis and AL amyloidosis.
    Type: Application
    Filed: October 25, 2012
    Publication date: November 7, 2013
    Applicant: ONCLAVE THERAPEUTICS
    Inventors: PATRICK GARIDEL, Isaac Craig Henderson, Pamela Klein
  • Chimeric, humanized, or human antibody 2A4
    Patent number: 8404815
    Abstract: Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: March 26, 2013
    Assignee: Onclave Therapeutics
    Inventors: Dale B. Schenk, Peter A. Seubert
  • Anti-amyloid antibodies
    Patent number: 8268973
    Abstract: Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: September 18, 2012
    Assignee: Onclave Therapeutics
    Inventors: Dale B. Schenk, Peter A. Seubert, José Saldanha