Patents Assigned to Onclave Therapeutics Limited
  • TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS
    Publication number: 20150158937
    Abstract: Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
    Type: Application
    Filed: June 25, 2014
    Publication date: June 11, 2015
    Applicant: ONCLAVE THERAPEUTICS LIMITED
    Inventors: Dale B. SCHENK, Peter A. SEUBERT, José SALDANHA
  • Treatment and prophylaxis of amyloidosis
    Patent number: 8791243
    Abstract: Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: July 29, 2014
    Assignee: Onclave Therapeutics Limited
    Inventors: Dale B. Schenk, Peter A. Seubert, Jonathan Wall, Jose Saldanha