Abstract: Disclosed are surprising new methods and kits for identifying and treating patients treatable with PS-targeting antibodies, particularly for identifying and treating cancer patients using bavituximab and bavituximab combination therapies. The methods and kits are based on the surprising finding that defined ranges of pre-treatment blood concentrations of ?2-glycoprotein 1 (?2GPI), particularly functional ?2GPI, act as an indicator to accurately predict patients with better treatment outcomes.
Type:
Application
Filed:
September 26, 2017
Publication date:
February 4, 2021
Applicant:
ONCOLOGIE, INC.
Inventors:
Min Tang, Joseph S. Shan, Steven W. King, Connie Chang, Michael A. Brown