Patents Assigned to Oncology Sciences Corporation
  • Patent number: 10080376
    Abstract: A process for enhancing polyphenolics content of beverages brewed from polyphenolic containing, processed beverage substrate by pre-soaking substrate (coffee beans, for example) before roasting and then quenching the substrate after processing with the liquid in which the substrate was first “pre-soaked.” Beverages produced from the treated substrate exhibit substantially increased polyphenolics content, when compared to conventionally processed beverage substrate of the same nature and processing.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: September 25, 2018
    Assignees: ONCOLOGY SCIENCES CORPORATION, THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Loretta Zapp, Thomas J. Slaga, Jifu Zhao, Mark Lange
  • Publication number: 20130129882
    Abstract: A process for enhancing polyphenolics content of beverages brewed from polyphenolic containing, processed beverage substrate by pre-soaking substrate (coffee beans, for example) before roasting and then quenching the substrate after processing with the liquid in which the substrate was first “pre-soaked.” Beverages produced from the treated substrate exhibit substantially increased polyphenolics content, when compared to conventionally processed beverage substrate of the same nature and processing.
    Type: Application
    Filed: January 15, 2013
    Publication date: May 23, 2013
    Applicants: AMC Cancer Research Center, Oncology Sciences Corporation
    Inventors: Oncology Sciences Corporation, AMC Cancer Research Center
  • Publication number: 20050003067
    Abstract: A process for enhancing polyphenolics content of beverages brewed from polyphenolic containing, processed beverage substrate by pre-soaking substrate (coffee beans, for example) before roasting and then quenching the substrate after processing with the liquid in which the substrate was first “pre-soaked.” Beverages produced from the treated substrate exhibit substantially increased polyphenolics content, when compared to conventionally processed beverage substrate of the same nature and processing.
    Type: Application
    Filed: April 20, 2004
    Publication date: January 6, 2005
    Applicant: Oncology Science Corporation
    Inventors: Loretta Zapp, Thomas Slaga, Jifu Zhao, Mark Lange
  • Publication number: 20040053906
    Abstract: The invention is of both a composition and method for inhibiting the proliferation of cancerous cells. The composition is, and the method is based on the use of a composition consisting (among active ingredients) substantially of 2-methoxyestradiol and/or one of a number of anaologues thereof. The present inventors have demonstrated beyond serious doubt that these compounds have a pronounced effect in inhibiting the proliferation of cancerous cells and, therefore, provide a desperately needed stepping stone for advancing toward meaningful treatment of cancer.
    Type: Application
    Filed: June 25, 2003
    Publication date: March 18, 2004
    Applicant: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar, William Allworth
  • Publication number: 20030073674
    Abstract: The use of 2-methoxyestradiol, analogues of 2-methoxyestradiol, their method of synthesis and therapeutic use, and the use of combinations of the 2 methoxyestradiol and its analogues, with and without synergistic compounds (namely eugenol), all in the prevention of initial onset cancers, treatment of existing cancers, and the recurrence of previously existing cancers.
    Type: Application
    Filed: September 17, 2002
    Publication date: April 17, 2003
    Applicant: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar, William Alworth
  • Publication number: 20030036539
    Abstract: The use of 2-methoxyestradiol in the prevention of initial onset cancers and the recurrence of previously existing cancers, through use of such compound in a manner to promoteo pro-apoptotic activities in target cells and tissues.
    Type: Application
    Filed: August 1, 2002
    Publication date: February 20, 2003
    Applicant: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar
  • Patent number: 6518261
    Abstract: The use of eugenol, alone and in combination with 2-methoxyestradiol (2-ME) in the context of prostate cancer prophylaxes and treatment.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: February 11, 2003
    Assignee: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar, William Alworth
  • Publication number: 20030027803
    Abstract: The invention is of both a composition and method for inhibiting the proliferation of cancerous cells, and brain and nervous system cells in particular. The composition is, and the method is based on the use of a composition consisting (among active ingredients) substantially of 2-methoxyestradiol and/or one of a number of analogues thereof. The present inventors have demonstrated beyond serious doubt that these compounds have a pronounced effect in inhibiting the proliferation of cancerous brain and nervous system cells and, therefore, provide a desperately needed stepping stone for advancing toward meaningful treatment of brain and nervous system cancer.
    Type: Application
    Filed: February 6, 2001
    Publication date: February 6, 2003
    Applicant: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar, William Alworth
  • Publication number: 20020160067
    Abstract: A raw green coffee bean extraction method and coffee extract end product. The method produces a coffee extract end product which contains antioxidants (phenolic compounds), diterpenes (having detoxification properties), has greater bioavailability and greater ability to quench oxidative stress in comparison to existing polyphenol extracts.
    Type: Application
    Filed: April 25, 2001
    Publication date: October 31, 2002
    Applicant: Oncology Science Corporation
    Inventors: Loretta M. Zapp, Alan Andrews, Lyndon C. Johnson, Brian J. Slaga
  • Publication number: 20020068724
    Abstract: The invention is of both a composition and method for inhibiting the proliferation of cancerous cells. The composition is, and the method is based on the use of a composition consisting (among active ingredients) substantially of 2-methoxyestradiol and/or one of a number of anaologues thereof. The present inventors have demonstrated beyond serious doubt that these compounds have a pronounced effect in inhibiting the proliferation of cancerous cells and, therefore, provide a desperately needed stepping stone for advancing toward meaningful treatment of cancer.
    Type: Application
    Filed: February 5, 2001
    Publication date: June 6, 2002
    Applicant: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar, William Alworth
  • Publication number: 20020035098
    Abstract: The use of 2-methoxyestradiol, analogues of 2-methoxyestradiol, their method of synthesis and therapeutic use, and the use of combinations of the 2 methoxyestradiol and its analogues with synergistic compounds (namely eugenol), all in the prevention of initial onset cancers and the recurrence of previously existing cancers.
    Type: Application
    Filed: March 14, 2001
    Publication date: March 21, 2002
    Applicant: Oncology Sciences Corporation
    Inventors: Thomas J. Slaga, Addanki P. Kumar, William Alworth