Patent number: 6579869
Abstract: The present invention concerns a compound of formula (I)
wherein:
W represents O or NH,
Q represents an unbranched or branched, saturated or unsaturated or aromatic, cyclic or acyclic or heterocyclic hydrocarbon radical containing 1 to 30 carbon atoms including or not heteroatom(s),
R1 is H, OH, or OMe, O-(C1-C30)-alkyl, O-aryl-(C1-C30)-alkyl, O-(C2-C30)-alkenyl, O-(C3-C30)-cycloalkyl or null, and
R2 is H or OH, or R1 and R2 form together —O—,
R3=R4=OMe or R3 and R4 form together —OCH2O—,
R is H, C1-C30 alkyl or O-protecting group and R6 represents an unbranched or branched, saturated or unsaturated or aromatic, cyclic or acyclic or heterocyclic hydrocarbon radical containing 1 to 30 carbon atoms including or not heteroatom(s), or R and R6 form together —CMe2—,
n is 0 to 8,
R5 is H, OH, OMe, O-(C1-C30)-alkyl, O-aryl-(C1-C30)-alkyl, O-(C2-C30)-alkenyl, O-(C3-C30)-cycloalkyl or O-aryl,
the dotted line is null or forms a double bond dep
Type:
Grant
Filed:
November 14, 2000
Date of Patent:
June 17, 2003
Assignee:
Oncopharm Corporation
Inventors:
Jean-Pierre Robin, Robert Dhal, Freddy Drouye, Jean-Pierre Marie, Nina Radosevic, Julie Robin, Karine Souchaud, Patricia Bataille