Patents Assigned to OncoPharmaceutical, Inc.
  • Inhibitors of angiogenesis and tumor growth for local and systemic administration
    Patent number: 6696483
    Abstract: The invention provides pharmaceutical formulations and methods for the treatment of individuals suffering from a condition, disease, or disorder that is treatable by the inhibition of angiogenesis. The compositions comprise a Golgi apparatus disturbing agent in a substantially nontoxic amount effective to inhibit angiogenesis in a patient in need of anti-angiogenesis therapy, a solvent, and a pharmaceutically acceptable carrier. In preferred formulations, the Golgi apparatus disturbing agent is brefeldin A.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: February 24, 2004
    Assignee: OncoPharmaceutical, Inc.
    Inventor: Saira Sayed Singh
  • Treatment of oncologic tumors with an injectable formulation of a Golgi apparatus disturbing agent
    Patent number: 6287602
    Abstract: Novel pharmaceutical formulations for treating a cellular proliferative disease are provided comprising: a therapeutically effective amount of a Golgi apparatus disturbing agent; a biocompatible carrier; and a solvent. In preferred formulations, the Golgi apparatus disturbing agent is brefeldin A (BFA) and the biocompatible carrier is a polymer such as chitin or chitosan. Methods of treating cellular proliferative diseases using the pharmaceutical formulations are also described.
    Type: Grant
    Filed: September 15, 1999
    Date of Patent: September 11, 2001
    Assignee: OncoPharmaceutical, Inc.
    Inventor: Saira Sayed Singh