Patents Assigned to Oncoscience AG
  • TREATMENT OF PATIENTS DIAGNOSED WITH PANCREATIC DUCTAL ADENOCARCINOMA USING USING MONOCLONAL ANTIBODIES AGAINST THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR)
    Publication number: 20180221478
    Abstract: The present disclosure relates to the field of immunotherapy of cancer, in particular pancreatic ductal adenocarcinoma (PDAC). Means and methods for treatment of a population of PDAC patients suffering from PDAC tumours which express wildtype KRAS, HRAS or NRAS are disclosed. The claimed antibody is Nimotuzumab. The pancreatic cancer preferably does not contain KRAS mutations at position 12, 16, 61, 154.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 9, 2018
    Applicants: INNOCIMAB PTE LTD, ONCOSCIENCE AG
    Inventors: Dirk STRUMBERG, Beate SCHULTHEIS, Matthias P. EBERT, Jens SIVEKE, Andrea KERKHOFF, Ralf HOFHEINZ, Dirk M. BEHRINGER, Wolfgang E. SCHMIDT, Erdem GOKER, Sara DE DOSSO, Michael KNEBA, Suayib YALCIN, Friedrich OVERKAMP, Frank SCHLEGEL, Markus DOMMACH, Robert ROHRBERG, Tilman STEINMETZ, Ferdinand BACH, Dirk REUTER, Rikrik Asiyah ILYAS, Normando E. IZNAGA ESCOBAR
  • Delocalization molecules and use thereof
    Patent number: 8362205
    Abstract: The invention relates to delocalization molecules, methods for the production thereof, and the use thereof as medicaments, especially for treating tumors.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: January 29, 2013
    Assignees: Oncoscience AG
    Inventors: Wolfgang Berdel, Carsten Müller-Tidow, Hubert Serve, Björn Steffen
  • Fusion polypeptides, and use thereof in antivascular tumor therapy
    Patent number: 7618943
    Abstract: The present invention relates to fusion polypeptides, comprising at least two peptides. The invention further relates to the use of these fusion proteins in antivascular therapy of neoplastic diseases and to their use I the production of a drug for the treatment of neoplastic diseases.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: November 17, 2009
    Assignee: Oncoscience AG
    Inventors: Wolfgang E. Berdel, Rolf M. Mesters
  • Method for sorting tumor cells
    Patent number: 7604933
    Abstract: The present invention relates to a method for storing cells, wherein the cells are stored in a composition comprising a base nutritive medium and liposomes at temperatures in the range of ?196° C. to 37° C., characterized in that the liposomes comprise one or more sterols and that the cells are tumor cells. More specifically, the invention relates to simple and effective methods for storing tumor cells, wherein the RNA and/or DNA in the cells is essentially not degraded, such that the RNA and/or DNA can be analyzed after storage.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: October 20, 2009
    Assignee: Oncoscience AG
    Inventors: Ferdinand Bach, Joseph Fischer