Abstract: An ablation device, the device comprising: a sheath; a plurality of needle electrodes that are each extendible from a distal end of the sheath; and a controller that is configured to selectively apply a power signal between specified pairs of needle electrodes of the plurality of needle electrodes, when the plurality of needle electrodes are in contact with a tissue, so as to ablate a desired region of said tissue.

Abstract: Apparatus, comprising: a sheath (22), advanceable through an endoscope (10), and having distal openings comprising a first opening (30a) and a plurality of second openings (30b) surrounding the first opening; a housing (24), coupled to a proximal portion of the sheath; a first needle (28a), extending through the housing and sheath toward the first opening; a plurality of second needles (28b), extending through the housing and sheath toward a respective second opening; a first handle (26a), slidably coupled to the housing along an axis such that the first needle slides through the sheath and a distal tip of the first needle moves with respect to the first opening; and a second handle (26b), slidably coupled to the housing along a different axis such that the second needles slide through the sheath and a distal tip of each second needle moves with respect to its respective second opening.

Abstract: An apparatus comprising: a sheath comprising a plurality of openings at a distal end; an elongate first needle extendible perpendicularly from said sheath through one of said plurality of openings; and an assembly comprising at least two second needles arranged in a predetermined pattern relative to said first needle, and extendible perpendicularly from said sheath, wherein, when extended from said distal end of said sheath: (i) each of said second needles extends a different length from said distal end of said sheath, (ii) at least a distal portion of each of said second needles is resiliently biased to extend laterally outwardly in relation to said first needle, and (iii) a lateral spread region defined by said distal portions of all of said second needles is determined based, at least in part, on a distance of said extending from said distal end of said sheath.

Abstract: Apparatus, comprising: a sheath (22), advanceable through an endoscope (10), and having distal openings comprising a first opening (30a) and a plurality of second openings (30b) surrounding the first opening; a housing (24), coupled to a proximal portion of the sheath; a first needle (28a), extending through the housing and sheath toward the first opening; a plurality of second needles (28b), extending through the housing and sheath toward a respective second opening; a first handle (26a), slidably coupled to the housing along an axis such that the first needle slides through the sheath and a distal tip of the first needle moves with respect to the first opening; and a second handle (26b), slidably coupled to the housing along a different axis such that the second needles slide through the sheath and a distal tip of each second needle moves with respect to its respective second opening.