Patents Assigned to Ontario Institute for Cancer Research Mars Centre
  • PROTECTION OF BARCODES DURING DNA AMPLIFICATION USING MOLECULAR HAIRPINS
    Publication number: 20180051277
    Abstract: Described herein are approaches for the improved detection, identification, and/or quantification of target nucleic acids. These approaches provide a means of detecting, identifying, and/or quantifying rare target nucleic acid molecules, including DNA and RNA molecules, from the same sample, and in the same reaction, by using “hairpin barcode primers,” as the term is defined herein, to incorporate unique barcodes into target nucleic acids in a PCR pre-amplification step.
    Type: Application
    Filed: February 24, 2016
    Publication date: February 22, 2018
    Applicants: Trustees of Boston University, Ontario Institute for Cancer Research Mars Centre
    Inventors: Tony Edward GODFREY, Anders Torbjoern STAAHLBERG, Paul KRZYZANOWSKI