Abstract: The present invention provides novel compounds of Formula 1 or Formula 2 and compositions thereof, methods of their use, and methods of their manufacture,
wherein X, Y, Z, W, R1, R2 and R3 are defined more fully in the description. These compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, and a number of other diseases.
Type:
Grant
Filed:
September 21, 1998
Date of Patent:
January 2, 2001
Assignees:
Novo Nordisk A/S, Ontogen
Inventors:
Henrik Sune Andersen, Sven Branner, Claus Bekker Jeppesen, Niels Peter Hundahl Moeller, Adnan M. M. Mjalli, Sepehr Sarshar