Abstract: A system, method and computer program product for protocol-independent processing of information in an enterprise integration application. The system includes host processors for managing flow of information throughout the system, channel processors for operatively communicating between processors in the system, and preexisting legacy processors. The system dynamically maintains uniform configuration of its topology and the means by which it routes information across the system in accordance with predefined business rules. In operation, processors interact with corresponding channel processors to intercommunicate legacy systems and the enterprise integration application system.