Patents Assigned to Ophthalmic Research Associates, Inc.
  • Formulations and methods for treating dry eye
    Publication number: 20070254841
    Abstract: Provided are methods and compositions for treating and preventing dry eye and/or increasing tear film break-up time.
    Type: Application
    Filed: January 25, 2007
    Publication date: November 1, 2007
    Applicant: Ophthalmic Research Associates, Inc.
    Inventors: George Ousler, Matthew Chapin, Mark Abelson
  • Use of neurotransmitters and neuropeptides for the treatment of dry eye diseases and related conditions
    Publication number: 20060270592
    Abstract: The invention further features novel methods and compositions for treating and preventing dry eye by administration of neurotransmitters and/or neuropeptides, optionally in formulation with various other agents, as well as kits for the use of such novel formulations and methods.
    Type: Application
    Filed: December 6, 2005
    Publication date: November 30, 2006
    Applicant: Ophthalmic Research Associates, Inc.
    Inventors: George Ousler, Matthew Chapin, Mark Abelson
  • Novel topical ophthalmic formulations
    Publication number: 20050239745
    Abstract: The invention features novel topical formulations of antiallergenic agents in formulation with various other agents (such as a tear substitute) that provide a comfortable formulation when instilled in the eye and has enhanced efficacy and duration of action. The invention further features novel methods of treating ocular allergy by topical application of antiallergenic agents in formulation with various other agents (such as a tear substitute), as well as kits for the use of such novel formulations and methods.
    Type: Application
    Filed: March 3, 2005
    Publication date: October 27, 2005
    Applicant: Ophthalmic Research Associates, Inc.
    Inventors: Mark Abelson, Paulo Gomes, Matthew Chapin
  • Preparation of ophthalmic compositions
    Patent number: 6828356
    Abstract: A method of preparing a polymeric demulcent-containing ophthalmic composition. The method includes immersing a polymeric demulcent in water or in an aqueous solution containing one or more ingredients, agitating the water or solution at 25 to 45° C. until the polymeric demulcent is dissolved to form a polymeric demulcent-containing solution, and optionally adding one or more other ingredients to the polymeric demulcent-containing solution.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: December 7, 2004
    Assignees: AST Products, Inc., Ophthalmic Research Associates, Inc.
    Inventors: Shih-Horng Su, Min-Shyan Sheu
  • Ophthalmic compositions
    Patent number: 6806364
    Abstract: An aqueous ophthalmic solution containing 0.2 to 2.5 percent by weight a polymeric demulcent, 0.045 to 0.065 percent by weight a calcium salt, and 0.14 to 1.4 percent by weight a phosphate salt. The solution has a viscosity of 20 to 150 centipoise and is buffered to a pH 5.5 to 8.5.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: October 19, 2004
    Assignees: AST Products, Inc., Ophthalmic Research Associates, Inc.
    Inventors: Shih-Horng Su, George W. Ousler, III
  • Instillation techniques for ophthalmic agents to enhance treatment effect
    Patent number: 6465506
    Abstract: The present invention provides methods for instilling an ophthalmic agent. One embodiment of a method according to the invention includes causing a patient to refrain from blinking for at least a specified period of time so as to effect the substantial break down of the patient's tear film covering the patient's eye and instilling an ophthalmic agent to the patient's eye.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: October 15, 2002
    Assignee: Ophthalmic Research Associates, Inc.
    Inventors: Mark B. Abelson, George W. Ousler, III