Abstract: Method for preparing glucuronyl-glucosamino-glycan sulphates exhibiting antilipasaemic activity, according to which the duodenum of pancreas of animals are subjected to a hydrolysis, the liquid is removed, precipitation is carried out with a quaternary ammonium, the precipitate is separated with a saline solution of NaCl, KCl or CH.sub.3 COONa, then filtering and adding the liquid with an alcohol causing the precipitation of the desired product.