Abstract: The present invention relates to different uses of an RHCC peptide and/or a fragment thereof. Said RHCC peptide and/or fragment thereof enables an uptake and association of a drug and/or a substance into a cavity of said peptide and/or fragment, for the delivery and release of such a substance and/or drug to a target site of interest, or for removal of a substance from a fluid or a non-fluid matter, such as from a bodily tissue or a bodily fluid. An RHCC peptide and/or a fragment thereof, may also in one context be used in the production of nanoparticles, or as a catalyst in a chemical reaction. In a preferred aspect, said RHCC peptide and/or fragment thereof, comprises a drug delivery system for the delivery of a drug to a site of interest in a living body.
Abstract: Disclosed is a coated suture thread comprising a matrix formed by an immobilized and crosslinked plurality of fibrinogen layers into and/or onto which one or several pharmacological substances that inhibit tissue break-down, such as MMP inhibitors and/or corticosteroids and/or COX inhibitors, are attached and/or associated. Further, a method of producing such a coated suture thread as well as the use thereof for suturing damaged tissue, such as damaged tendon, ligament, intestine and/or skin, are described.
Type:
Application
Filed:
February 21, 2006
Publication date:
July 9, 2009
Applicant:
Optovent AB
Inventors:
Per Vilhelm Aspenberg, Pentti Tengvall, Björn Pasternak
Abstract: The invention relates to an elastomeric device (105), wherein the elastomeric device contains a relief structure with indentations with respect to the base (110), (102) and wherein selected ones of said indentations comprise at least two indentation depths (112), (108) and indentation widths (101), (107). It also relates to a method of making a master for construction of said elastomeric device comprising a procedure to provide a pattern on a substrate of a suitable material. One step in. the construction of said elastomeric device comprises a molding procedure of an elastomer. Methods of using the elastomeric device in printing, fluidic control, sorting, lab-on-a-chip devices are also disclosed.
Type:
Application
Filed:
March 8, 2006
Publication date:
February 26, 2009
Applicants:
OPTOVENT AB, Forskarpatent i Linkoping AB
Inventors:
Mahiar Hamedi, Kristofer Tvingstedt, Peter Asberg, Olle Inganas
Abstract: The method of the present invention is for coating an implant device. The implant device is coated with a protein film, such as fibrinogen. A first bisphosphonate substance, such as pamidronate, is immobilized to the protein film. A second bisphosphonate substance, such ibandronate, is adsorbed to the first bisphosphonate wherein the first bisphosphonate is different from the second bisphosphonate.
Type:
Grant
Filed:
July 1, 2004
Date of Patent:
January 16, 2007
Assignee:
Optovent AB
Inventors:
Per Vilhelm Aspenberg, Pentti Olavi Tengvall
Abstract: A method, a device and a sensor to sense the breathing of a man or an animal. A breathing sensor which, in an optical way, detects changes in deposited moisture on a sensor portion is placed in the breathing air flow, and changes of a transmitted or reflected optical signal dependent on deposited moisture is sensed as a measure of the breathing. A sensor according to the invention may consist of an optical fiber, one end surface of which constitutes a sensor surface and reflects a signal in the fiber to a varying degree dependent on mist deposited by the breathing air flow on the sensor surface. The sensor can be used in other environments as well, to detect a condensable vapor in a gas.