Patents Assigned to Or-Nim Medical Ltd.
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Patent number: 9237850Abstract: A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.Type: GrantFiled: February 22, 2012Date of Patent: January 19, 2016Assignee: OR-NIM MEDICAL LTD.Inventors: Yaacov Metzger, Michal Rokni, Revital Pery-Shechter
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Patent number: 9131880Abstract: Apparatus and methods are provided including directing acoustic radiation toward a region of interest within a subject's body. Light is transmitted from a light emitter to a light detector such that a first light portion is transmitted without passing through the subject's tissue, and a second light portion is transmitted via the region of interest. Scattered light of the second light portion contains a tagged component corresponding to photons tagged by the acoustic radiation, and an untagged component corresponding to photons untagged by the acoustic radiation. Light of the first light portion undergoes an interaction with light of the second light portion at the light detector. A property of tissue of the region of interest is determined, by decoupling from each other the tagged and untagged components of the second light portion, based upon the interaction between the light of the first and second light portions.Type: GrantFiled: March 25, 2013Date of Patent: September 15, 2015Assignee: OR-NIM MEDICAL LTD.Inventors: Michal Balberg, Revital Pery-Shechter
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Patent number: 9078617Abstract: A probe assembly is presented for use in monitoring one or more parameters of a subject. The probe assembly comprises: an acoustic port for transmitting acoustic radiation into a region of interest in the subject, at least one light output port for transmitting incident light towards the region of interest, at least one light input port for receiving light returned from the subject, and a control utility integrated in the probe assembly, said control utility being configured for controlling at least one condition of a monitoring procedure and enabling the monitoring procedure upon detecting that said at least one condition is satisfied.Type: GrantFiled: March 12, 2009Date of Patent: July 14, 2015Assignee: OR-NIM MEDICAL LTD.Inventors: Ofer Pintel, Michael Bendkowski, Ilan Breskin, Yaakov Metzger, Revital Pery Shechter
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Patent number: 9027412Abstract: A fluid flow monitoring system is provided that has a processor utility which is connectable to an acoustic generator associated with acoustic ports and is operable for generating signals S0 to activate the acoustic ports for irradiating a region of interest with acoustic radiation of a certain frequency range centered at a frequency F0 and is connectable to at least one light output port associated with one or more light detectors for receiving light of at least one wavelength ? from the region of interest including light tagged by said acoustic radiation. The processor utility may be configured for analyzing the generated signals S0 and data indicative of the received light including light tagged by the corresponding acoustic radiation and determining correlation between the signals S0 and the data indicative of the received light, the correlation being informative of a measure of fluid flow in a turbid medium.Type: GrantFiled: December 11, 2012Date of Patent: May 12, 2015Assignee: Or-Nim Medical Ltd.Inventors: Michal Rokni, Revital Pery Shechter, Ilan Breskin, Michal Balberg, Yaakov Metzger
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Method and apparatus for noninvasively monitoring parameters of a region of interest in a human body
Patent number: 8644900Abstract: Apparatus and methods are provided for monitoring a parameter of a region of interest (ROI) within a first tissue type within a body. A control unit drives a measurement unit to provide an operating condition such that acoustic waves overlap with a region within the ROI that is illuminated by illuminating light such as to generate a first set of tagged photons, and such that the acoustic waves overlap with a region of tissue within a second tissue type that is illuminated by illuminating light such as to generate a second set of tagged photons, the first and second sets of tagged photons being distinguishable from one another. The control unit determines the parameter of the ROI by extracting data portions associated with, respectively, the light response of the ROI and the light response of the second tissue type, by distinguishing between the sets of tagged photons.Type: GrantFiled: January 23, 2012Date of Patent: February 4, 2014Assignee: Or-Nim Medical Ltd.Inventors: Michal Balberg, Revital Pery-Schechter, Michal Olshansky -
Publication number: 20130317326Abstract: Apparatus and methods are provided including directing acoustic radiation toward a region of interest within a subject's body. Light is transmitted from a light emitter to a light detector such that a first light portion is transmitted without passing through the subject's tissue, and a second light portion is transmitted via the region of interest. Scattered light of the second light portion contains a tagged component corresponding to photons tagged by the acoustic radiation, and an untagged component corresponding to photons untagged by the acoustic radiation. Light of the first light portion undergoes an interaction with light of the second light portion at the light detector. A property of tissue of the region of interest is determined, by decoupling from each other the tagged and untagged components of the second light portion, based upon the interaction between the light of the first and second light portions.Type: ApplicationFiled: March 25, 2013Publication date: November 28, 2013Applicant: OR-NIM Medical Ltd.Inventor: OR-NIM Medical Ltd.
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Publication number: 20130151188Abstract: A fluid flow monitoring system is provided that has a processor utility which is connectable to an acoustic generator associated with acoustic ports and is operable for generating signals S0 to activate the acoustic ports for irradiating a region of interest with acoustic radiation of a certain frequency range centered at a frequency F0 and is connectable to at least one light output port associated with one or more light detectors for receiving light of at least one wavelength ? from the region of interest including light tagged by said acoustic radiation. The processor utility may be configured for analyzing the generated signals S0 and data indicative of the received light including light tagged by the corresponding acoustic radiation and determining correlation between the signals S0 and the data indicative of the received light, the correlation being informative of a measure of fluid flow in a turbid medium.Type: ApplicationFiled: December 11, 2012Publication date: June 13, 2013Applicant: OR-NIM MEDICAL LTD.Inventor: OR-NIM MEDICAL LTD.
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Patent number: 8423116Abstract: A measurement system and method are presented for use for non-invasive measurements in a human body. Acoustic radiation is applied to a certain illuminated region in the body, with at least two different conditions of the applied radiation achievable by varying at least one characteristic of the acoustic radiation. Light scattered from the body part is detected, and measured data indicative of detected photons tagged and untagged by the acoustic radiation is generated. The measured data is analyzed to extract therefrom a data portion corresponding to the tagged photons and being therefore associated with a light response of said certain region, thereby enabling determination of tissue properties of said certain region based on a relation between the measured data portions corresponding to the at least two different operating conditions.Type: GrantFiled: March 16, 2005Date of Patent: April 16, 2013Assignee: Or-Nim Medical Ltd.Inventors: Michal Balberg, Revital Pery-Shechter, Michal Olshansky
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Patent number: 8336391Abstract: A monitoring system is presented for monitoring fluid flow in turbid medium. The fluid flow monitoring system comprises a processor utility which is connectable to an acoustic generator associated with one or more acoustic ports and is operable for generating signals S0 to activate said one or more acoustic ports for irradiating a region of interest with acoustic radiation of a certain frequency range centered at a frequency F0 and is connectable to at least one light output port associated with one or more light detectors for receiving light of at least one wavelength ? from the region of interest including light tagged by said acoustic radiation.Type: GrantFiled: July 6, 2009Date of Patent: December 25, 2012Assignee: OR-NIM Medical Ltd.Inventors: Michal Rokni, Revital Pery Shechter, Ilan Breskin, Michal Balberg, Yaakov Metzger
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METHOD AND APPARATUS FOR NONINVASIVELY MONITORING PARAMETERS OF A REGION OF INTEREST IN A HUMAN BODY
Publication number: 20120184830Abstract: Apparatus and methods are provided for monitoring a parameter of a region of interest (ROI) within a first tissue type within a body. A control unit drives a measurement unit to provide an operating condition such that acoustic waves overlap with a region within the ROI that is illuminated by illuminating light such as to generate a first set of tagged photons, and such that the acoustic waves overlap with a region of tissue within a second tissue type that is illuminated by illuminating light such as to generate a second set of tagged photons, the first and second sets of tagged photons being distinguishable from one another. The control unit determines the parameter of the ROI by extracting data portions associated with, respectively, the light response of the ROI and the light response of the second tissue type, by distinguishing between the sets of tagged photons.Type: ApplicationFiled: January 23, 2012Publication date: July 19, 2012Applicant: Or-Nim Medical Ltd.Inventors: Michal BALBERG, Revital Pery-Schechter, Michal Olshansky -
Publication number: 20120150014Abstract: A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.Type: ApplicationFiled: February 22, 2012Publication date: June 14, 2012Applicant: Or-Nim Medical Ltd.Inventors: Yaacov METZGER, Michal Rokni, Revital Pery-Shechter
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Patent number: 8143605Abstract: A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.Type: GrantFiled: June 1, 2009Date of Patent: March 27, 2012Assignee: Or-Nim Medical Ltd.Inventors: Yaacov Metzger, Michal Rokni, Revital Pery-Shechter
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Method and apparatus for noninvasively monitoring parameters of a region of interest in a human body
Patent number: 8126524Abstract: A method and system for noninvasive monitoring of at least one parameter of a region of interest in a human body. The system comprises a measurement unit and a control unit. The measurement unit comprises an optical unit having an illumination assembly (101A) and a light detection assembly (101B) to generate measured data indicative of collected light; and an acoustic unit (110) configured to generate acoustic waves of a predetermined ultrasound frequency range. The measurement unit provides an operating condition such that the acoustic waves overlap with an illuminating region within the region of interest and substantially do not overlap outside the region of interest. The measured data is indicative of scattered light having both ultrasound tagged and untagged light portions, enabling to distinguish between light responses of the region of interest and the region outside the region of interest.Type: GrantFiled: September 12, 2004Date of Patent: February 28, 2012Assignee: Or-Nim Medical Ltd.Inventors: Michal Balberg, Revital Pery-Shechter, Michal Olshansky -
Method and apparatus for noninvasively monitoring parameters of a region of interest in a human body
Patent number: 8108022Abstract: Apparatus and methods including a probe device for monitoring a parameter of a region of interest in a human body. A support structure of the device carries an arrangement of light output ports of a light source assembly, light input ports of a light detection assembly, and an acoustic output port of an acoustic unit. The arrangement is such as to enable selection of a light output port, a light input port, and an acoustic output port for an operating condition at which, acoustic waves from the acoustic output port and illuminating light from the light output port overlap in a region within the region of interest in the body thereby inducing tagging of light by the acoustic waves, and the light input port collects light scattered from the overlapping region and light scattered from outside the region of interest. Other embodiments are also described.Type: GrantFiled: January 9, 2006Date of Patent: January 31, 2012Assignee: OR-NIM Medical Ltd.Inventors: Michal Balberg, Revital Pery-Schechter, Michal Olshansky -
Publication number: 20100000330Abstract: A monitoring system is presented for monitoring fluid flow in turbid medium. The fluid flow monitoring system comprises a processor utility which is connectable to an acoustic generator associated with one or more acoustic ports and is operable for generating signals S0 to activate said one or more acoustic ports for irradiating a region of interest with acoustic radiation of a certain frequency range centered at a frequency F0 and is connectable to at least one light output port associated with one or more light detectors for receiving light of at least one wavelength ? from the region of interest including light tagged by said acoustic radiation.Type: ApplicationFiled: July 6, 2009Publication date: January 7, 2010Applicant: OR-NIM MEDICAL LTD.Inventors: Michal ROKNI, Revital Pery SHECHTER, IIan BRESKIN, Michal BALBERG, Yaakov METZGER
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Publication number: 20090264722Abstract: A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.Type: ApplicationFiled: June 1, 2009Publication date: October 22, 2009Applicant: Or-Nim Medical Ltd.Inventors: Yaacov Metzger, Michal Rokni, Revital Pery-Shechter
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Publication number: 20090234228Abstract: A probe assembly is presented for use in monitoring one or more parameters of a subject. The probe assembly comprises: an acoustic port for transmitting acoustic radiation into a region of interest in the subject, at least one light output port for transmitting incident light towards the region of interest, at least one light input port for receiving light returned from the subject, and a control utility integrated in the probe assembly, said control utility being configured for controlling at least one condition of a monitoring procedure and enabling the monitoring procedure upon detecting that said at least one condition is satisfied.Type: ApplicationFiled: March 12, 2009Publication date: September 17, 2009Applicant: OR-NIM MEDICAL LTD.Inventors: Ofer PINTEL, Michael BENDKOWSKI, Ilan BRESKIN, Yaakov METZGER, Revital Pery Suechter
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Patent number: 7541602Abstract: A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.Type: GrantFiled: June 4, 2007Date of Patent: June 2, 2009Assignee: Or-Nim Medical Ltd.Inventors: Yaacov Metzger, Michal Rokni, Revital Pery-Shechter
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Publication number: 20080312533Abstract: A measurement system and method are presented for use for non-invasive measurements in a human body. Acoustic radiation is applied to a certain illuminated region in the body, with at least two different conditions of the applied radiation achievable by varying at least one characteristic of the acoustic radiation. Light scattered from the body part is detected, and measured data indicative of detected photons tagged and untagged by the acoustic radiation is generated. The measured data is analyzed to extract therefrom a data portion corresponding to the tagged photons and being therefore associated with a light response of said certain region, thereby enabling determination of tissue properties of said certain region based on a relation between the measured data portions corresponding to the at least two different operating conditions.Type: ApplicationFiled: March 16, 2005Publication date: December 18, 2008Applicant: OR-NIM MEDICAL LTD.Inventors: Michal Balberg, Revital Pery-Shechter, Michal Olshansky
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Publication number: 20080296514Abstract: A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.Type: ApplicationFiled: June 4, 2007Publication date: December 4, 2008Applicant: Or-Nim Medical Ltd.Inventors: Yaacov Metzger, Michal Rokni, Revital Perry-Shechter