Abstract: The invention provides a method of preventing, inhibiting or reducing a P. gingivalis biofilm in a subject comprising administering to the subject a pharmaceutical composition comprising an inhibiting agent of a polypeptide that reduces or inhibits biofilm formation and/or biofilm development. Also provided are compositions useful in the prevention, inhibition or treatment of periodontal disease or P. gingivalis infection.
Type:
Grant
Filed:
July 11, 2008
Date of Patent:
August 14, 2012
Assignee:
Oral Health Austrailia Pty. Ltd.
Inventors:
Stuart Geoffrey Dashper, Eric Charles Reynolds, Paul David Veith, Ching Seng Ang