Abstract: The disclosure relates to ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt. Aspects of the disclosure further relate to uses and preparations of ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt, for correcting presbyopia and other ocular conditions in a subject.
Type:
Grant
Filed:
July 27, 2021
Date of Patent:
May 7, 2024
Assignee:
Orasis Pharmaceuticals Ltd.
Inventors:
Claes Feinbaum, Franc Salamun, Sudhir Patel
Abstract: The disclosure relates to ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt. Aspects of the disclosure further relate to uses and preparations of ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt, for correcting presbyopia and other ocular conditions in a subject.
Type:
Grant
Filed:
March 26, 2020
Date of Patent:
September 28, 2021
Assignee:
ORASIS PHARMACEUTICALS LTD.
Inventors:
Claes Feinbaum, Franc Salamun, Sudhir Patel
Abstract: The disclosure relates to ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt. Aspects of the disclosure further relate to uses and preparations of ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt, for correcting presbyopia and other ocular conditions in a subject.
Type:
Grant
Filed:
July 10, 2018
Date of Patent:
May 5, 2020
Assignee:
Orasis Pharmaceuticals Ltd.
Inventors:
Claes Feinbaum, Franc Salamun, Sudhir Patel
Abstract: Drainage of body fluid from an area of undesirably high pressure can be accomplished by interconnecting an artificial non-blood fluid conduit with the vascular system. For example, an artificial non-blood fluid conduit can be inserted into the eye to fluidly interconnect the anterior chamber with a location of lower pressure. The conduit can have a growth factor for stimulating growth of new blood vessels in the location of lower pressure to connect the new blood vessels with the non-blood fluid conduit.
Abstract: The disclosure relates to ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt. Aspects of the disclosure further relate to uses and preparations of ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt, for correcting presbyopia and other ocular conditions in a subject.
Type:
Grant
Filed:
August 18, 2017
Date of Patent:
January 16, 2018
Assignee:
Orasis Pharmaceuticals Ltd.
Inventors:
Claes Feinbaum, Franc Salamun, Sudhir Patel
Abstract: Methods are disclosed for treating glaucoma by treating a novel target. Methods for treating glaucoma by restoring the filtration capabilities of the endothelial lining of Schlemm's canal are provided. A method for identifying compounds capable of restoring the filtration capability of the juxtacanalicular meshwork is also provided.
Abstract: Methods are disclosed for treating glaucoma by treating a novel target. Methods for treating glaucoma by restoring the filtration capabilities of the endothelial lining of Schlemm's canal are provided. A method for identifying compounds capable of restoring the filtration capability of the juxtacanalicular meshwork is also provided.