Abstract: Disinfection device against viruses, bacteria and other microorganisms using ozone without contaminating the environment with ozone or users cross contamination. Disinfection is obtained by inserting an organ (e.g. hands) into a chamber containing a predetermined ozone concentration for a predetermined time. A suction duct surrounds the chamber. Ambient air mixed with overflow ozone from the chamber is fed through the suction duct into an ozone filter, then to an air outlet so the discharged air meets FDA regulation. The top of the chamber can be permanently open for inserting hands without ozone being discharged to the environment.