Patents Assigned to Orca Biosystems, Inc.
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Patent number: 12226770Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.Type: GrantFiled: August 4, 2023Date of Patent: February 18, 2025Assignee: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
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Patent number: 12011461Abstract: The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional ??-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.Type: GrantFiled: November 6, 2020Date of Patent: June 18, 2024Assignee: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Kevin Sheehan
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Publication number: 20240075471Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.Type: ApplicationFiled: August 4, 2023Publication date: March 7, 2024Applicant: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
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Patent number: 11759779Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.Type: GrantFiled: September 12, 2022Date of Patent: September 19, 2023Assignee: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
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Patent number: 11471885Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.Type: GrantFiled: June 16, 2020Date of Patent: October 18, 2022Assignee: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
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Patent number: 10857183Abstract: The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional ??-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.Type: GrantFiled: April 18, 2019Date of Patent: December 8, 2020Assignee: ORCA BIOSYSTEMS, INC.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Kevin Sheehan
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Patent number: 10722885Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.Type: GrantFiled: May 29, 2019Date of Patent: July 28, 2020Assignee: ORCA BIOSYSTEMS, INC.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
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Patent number: 10350595Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.Type: GrantFiled: July 24, 2018Date of Patent: July 16, 2019Assignee: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
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Patent number: 10300090Abstract: The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional ??-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.Type: GrantFiled: March 15, 2018Date of Patent: May 28, 2019Assignee: Orca Biosystems, Inc.Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Kevin Sheehan