Patents Assigned to ORCA PHARMACEUTICALS LIMITED
  • Indazole and indole derivatives as inhibitors of retinoic acid related orphan receptor gamma (ROR gamma) for the treatment of immune-related diseases
    Patent number: 10383850
    Abstract: The present invention provides compounds of formula (I), wherein A1, A2, Z1, Z2, Z3, R1, R2, R3, R4, R5, R6, n, p and q are as defined herein. In certain embodiments, the compounds of the invention are ROR?t antagonists. In other embodiments, the compounds of the invention are useful in the treatment and/or prevention of inflammatory and autoimmune conditions.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: August 20, 2019
    Assignee: ORCA PHARMACEUTICALS LIMITED
    Inventors: Clive McCarthy, Naomi Went, Roine Inge Olsson
  • Indolyl-containing ROR?t inhibitors
    Patent number: 9861612
    Abstract: The invention relates to compounds of formula (I), wherein R1 and R2 are as defined herein. The compounds of the invention are inhibitors of ROR?t and are useful in the treatment of diseases and conditions mediated by ROR?t.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: January 9, 2018
    Assignee: ORCA PHARMACEUTICALS LIMITED
    Inventors: Clive McCarthy, Naomi Went, Roine Inge Olsson
  • Compounds
    Patent number: 9522134
    Abstract: The present invention relates to compounds of formula (I): wherein R1 and R2 are as defined herein. In certain embodiments, the compounds of the present invention are inhibitors of ROR?t and are useful in the treatment of diseases and conditions mediated by ROR?t.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: December 20, 2016
    Assignee: ORCA PHARMACEUTICALS LIMITED
    Inventors: Clive McCarthy, Naomi Went, Roine Inge Olsson