Abstract: Tetrazine non-canonical amino acids, methods for making the tetrazine non-canonical amino acids, methods for incorporating the tetrazine non-canonical amino acids into proteins and polypeptides, post-translationally modified proteins and polypeptides in which the tetrazine non-canonical amino acids have been incorporated, and kits for incorporating the tetrazine non-canonical amino acids into proteins and polypeptides.

Abstract: Methods for inducing growth inhibition or apoptosis of Bcl-2-expressing cells and treatments of Bcl-2 expressing cancers are provided. Additionally, assays for agents that can induce apoptosis of Bcl-2 expressing cells are disclosed.

Abstract: A retinomorphic sensor is demonstrated employing organic semiconductors. The sensor produces an output voltage in response to changes in illumination, but zero output voltage under constant illumination. The device is stable for periods up to one hour, exhibits a decay constant tunable through choice of external resistor, with fastest response times below 10 ?s.

Abstract: Amide lipid conjugates of benzyl isothiocyanates are disclosed. The benzyl isothiocyanate is conjugated to a fatty acid, such as a C12-C26 fatty acid. The disclosed amide lipid conjugates have a structure according to Formula I, where one of R1A and R1B is alkoxy or hydroxy, and the other of R1A and R1B is —H; and R2 is C12-C26 aliphatic. Sunscreen formulations include a compound according to Formula I and one or more excipients. The sunscreen formulation may further include one or more additional sunscreen active agents.

Abstract: Various embodiments of a magneto-acoustic spin-wave signal processing system are provided. In one embodiment, a system includes an acoustic wave transducer configured to produce surface acoustic waves in a plane of a magnetostrictive material, wherein the magnetostrictive material serves as a medium for spin waves traveling in the plane, and wherein the acoustic wave transducer is oriented such that the acoustic waves parametrically amplify the spin waves. In this way, signal processing systems achieve the benefits of both spin wave and acoustic wave devices, taking advantage of the low dispersion and high dynamic range of acoustic waves coupled with the tunability and nonlinear effects provided by spin waves.

Abstract: The present invention provides in certain embodiments comprising a pyrrolysine-based aminoacyl-tRNA synthetase and a tRNA to form a pyrrolysine-based aminoacyl-tRNA synthetase/tRNA pair. The present invention also provides novel pyrrolysine-based aminoacyl-tRNA synthetases, cells and compositions comprising pyrrolysine-based aminoacyl-tRNA synthetases. The present invention also provides methods of using these pyrrolysine-based aminoacyl-tRNA synthetases.

Abstract: Reagents and aqueous solutions thereof are described that are useful for aqueous processing to form thin films comprising metal oxides. A film, or layered film, may be incorporated into working devices where the thin film provides useful optical properties, electrical properties, or both.

Abstract: Reaction assemblies, reactor systems including the same, and associated methods are disclosed. In an example, a reaction assembly includes a reaction assembly housing, a moving bed region, a gas acceleration region, and a reactive bed region. The gas acceleration region includes a nozzle configured to accelerate a reaction gas and one or more downcomer regions defined between the nozzle and the reaction assembly housing. A flow of reaction gas is accelerated within the gas acceleration region to produce a fluidizing gas flow to facilitate a chemical reaction between the reaction gas and reaction particles within the reactive bed region. A reactor system can include a reactor enclosure, a reaction particle inlet, a reaction gas inlet, and a reaction assembly. A method can include introducing a flow of reaction particles and a flow of reaction gas into a reactor enclosure and flowing the reaction gas in contact with the reaction particles.

Abstract: An ultraviolet radiation-curable composition comprising a polyester having at least one pendant ultraviolet radiation-curable moiety covalently bonded to the polyester, wherein the polyester does not contain any free-radically polymerizable activated C?C groups.

Abstract: Briefly, embodiments of an apparatus including at least one computing device that includes at least one processor and at least one non-transitory storage medium, for example, are described. The at least one non-transitory storage medium, in an embodiment, includes executable instructions stored thereon in which executing the instructions by the at least one processor are to result in processing sensor measurements, including images, from at least one optical sensor array, of at least one object. In an embodiment, for example, sensor measurements are processed with a three-dimensional pose estimation model to produce at least one substantially view-invariant morphometric measurement estimate of the at least one object.

Abstract: A new and distinct Corylus avellana plant is disclosed, distinguished by its low vigor, globose growth habit, production of nuts with round kernels that fall free of the husk at maturity, resistance to eastern filbert blight and big bud mite, S-alleles, nut size, kernel percentage, frequency of nut defects, time of pollen shed, and length of the husk or involucre.

Abstract: Described is an apparatus and ultrabroadband photoconduction microscopy method for measuring full sub-bandgap density of defect states in semiconductor transistors and devices. The apparatus comprises tunable laser coupled to a reflective-optic-based microscope using all-reflective optical laser to spectrally and spatially illuminate near the diffraction-limit. The method developed measures the photoconduction signal in semiconductor devices at stepwise incident energies that roughly span the full bandgap from the valence band to the conduction band edge regions. The resulting photoconduction spectrum is directly proportional to the integrated trap density by an analytically extracted scaling factor. Finally, the end-product is a complete sub-gap density of states for a semiconductor device.

Abstract: Disclosed herein are embodiments of a nanoparticle composition suitable for delivering a therapeutic agent to a subject by nebulization. The nanoparticle comprises an ionizable lipid, cholesterol or a derivative thereof, a structural lipid, and a PEG lipid. The nanoparticle may partially or completely encapsulate a therapeutic agent, and may be nebulized for administration, such as by inhalation. In some embodiments, the therapeutic agent is mRNA.

Abstract: This disclosure is directed to devices for the separation of mixtures of fluid phases. In some aspects of the disclosure, the separation device comprises an angled capillary cell. In other aspects, the separation device comprises a plurality of angled capillary cells operating in parallel. In some aspects of the disclosure, the separation device may be monolithically formed by an additive manufacturing process, such as three-dimensional printing. In some aspects of the disclosure, the separation device may function independently of gravitational direction, and without the use of filters.

Abstract: A nanoparticle for delivering an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor to a subject and methods for treating inflamed tissue in a subject using the nanoparticle.

Abstract: Novel compounds having a thortveitite-related structure are disclosed. The compounds may be colored and may be useful as pigments. The compounds are durable with respect to an acid stability test that indicates that the pigments will not substantially change color when exposed to weak acids, such as rain. The compounds disclosed herein typically inexpensive to synthesize from earth-abundant, environmentally-friendly elements or minerals, and therefore are advantageous over existing pigments in the art.

Abstract: Disclosed herein is a loading apparatus for restoration and/or cryopreservation of biological materials, a system comprising the same, as well as a method for using the loading apparatus and/or system to restore and/or cryopreserve biological materials. The disclosed loading apparatus and method for using the same focuses on utilizing cycles of applying and removing a load (e.g., tension and/or compression pressure) applied to the biological material that facilitate free-swelling of the biological material back to its natural state without the applied load, wherein the free-swelling promotes dispersion of a cryopreservation agent, therapeutic agent, restoration agent, or a combination thereof throughout the surface area of the biological material.

Abstract: Provided are antisense oligomers targeted against bacterial mRNAs and other macromolecules associated with a biochemical pathway and/or cellular process, and related compositions and methods of using the oligomers and compositions to treat an infected mammalian subject, for example, as primary antimicrobials or as adjunctive therapies with classic antimicrobials.

Abstract: Briefly, embodiments, such as estimating energy utilization based at least in part on estimated regenerative energy production to select one or more preferred routes for an electric vehicle out of a network of routes, for example, are described.

Abstract: A new and distinct Styrax japonicus plant named ‘ORSTSTYx1’ is disclosed, characterized by its strict weeping habit, purple foliage, pink flowers, and vigorous growth.