Abstract: Diagnostic methods for identifying cancer bearing subjects appropriate for treatment with CPX-351 include genetic and ex vivo testing of cells from a candidate subject. Combination treatment with CPX-351 and FLT-3 inhibitors improve CPX-351 uptake and toxicity.
Type:
Grant
Filed:
November 10, 2016
Date of Patent:
February 23, 2021
Assignees:
Celator Pharmaceuticals, Inc., Oreoon Health & Science University
Inventors:
Max Gordon, Paul Tardi, Jeffrey Tyner, Lawrence Mayer