Patents Assigned to Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H.
  • Patent number: 4895932
    Abstract: This invention teaches a method for determining the hormone cardiodilatin active fragments thereof, well as antibodies thereto.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: January 23, 1990
    Assignee: Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H.
    Inventor: Wolf-Georg Forssmann
  • Patent number: 4751284
    Abstract: There is described a new peptide hormone (cardiodilatin) and a process for its preparation, with the amino acid sequence: Asn-Pro-Val-Tyr-Gly-Ser-Val-Ser-Asn-Ala-Asp-Leu-Met-Asp-Phe-Lys-Asn-Leu-Le u-Asp-His-Leu-Glu-Asp-Lys-Met-Pro-Leu-Glu-Asp-Glu-Ala-Met-Pro-Pro-Gln-Val-L eu-Ser-Glu-Gln-Asp-Glu-Glu-Val-Gly-Ala-Pro-Leu-Pro-Leu-Leu-Glu-Glu-Val-Pro- Pro-Trp-Thr-Gly-Glu-Val-A n-Pro of the composition Asp/Asn 14, Thr 3, Ser 15, Glu/Gln 12, Pro 10, Gly 12, Ala 10, Val 7, Met 4, Ile 1, Leu 15, Tyr 2, Phe 3, Lys 4, His 2, Arg 10, Trp 2, a molecular weight of 13000 Dalton and an isoelectric point I.P. of 6 to 6.5.The peptide hormone, as well as its C-terminal fragments obtained after partial cyanogen bromide fission between and behind Met groups, possess a high relaxing action on the smooth bloodvessel musculature.
    Type: Grant
    Filed: August 20, 1985
    Date of Patent: June 14, 1988
    Assignee: Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H
    Inventor: Wolf-Georg Forssmann
  • Patent number: 4716122
    Abstract: The present invention provides a carrier such as polyethylene having covalently bound to it a reaction component such as an antibody, for use for immune determinations. The reaction component is covalently bound via heterobifunctional photoactivatable compounds, one group of which is found by an aryl azide group. Protein A may be bound covalently to the carrier via heterobifunctional photoactivatable compounds, and antibodies bound to the protein A.
    Type: Grant
    Filed: September 26, 1985
    Date of Patent: December 29, 1987
    Assignee: Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H.
    Inventor: Hans Scheefers