Patents Assigned to ORGENTEC DIAGNOSTIKA GMBH
  • Patent number: 11199553
    Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: December 14, 2021
    Assignee: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Vukic Soskic, Robert Poppe
  • Patent number: 10571464
    Abstract: The invention relates to methods, reagents and devices for detecting an analyte in a sample.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: February 25, 2020
    Assignee: Orgentec Diagnostika GmbH
    Inventors: Vinzenz Kirste, Wigbert Berg, Vukic Soskic
  • Publication number: 20190101548
    Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 4, 2019
    Applicant: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Vukic SOSKIC, Robert POPPE
  • Patent number: 10222388
    Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: March 5, 2019
    Assignee: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Vukic Soskic, Robert Poppe
  • Patent number: 9863963
    Abstract: The present invention relates to a method for releasing bound vitamin D by bringing a sample containing vitamin D into contact with a release reagent which contains at least one hydrotropic substance and at least one transition metal salt. The released vitamin D can subsequently be determined quantitatively. The present invention relates further to a reagent for releasing and optionally determining vitamin D, containing at least one hydrotropic substance and at least one transition metal salt, as well as to the use of such a release reagent for releasing and optionally determining vitamin D.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: January 9, 2018
    Assignee: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Robert Poppe, Vukic Soskic
  • Publication number: 20170115313
    Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.
    Type: Application
    Filed: August 1, 2014
    Publication date: April 27, 2017
    Applicant: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Vukic SOSKIC, Robert POPPE
  • Publication number: 20160195556
    Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.
    Type: Application
    Filed: August 1, 2014
    Publication date: July 7, 2016
    Applicant: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Vukic SOSKIC, Robert POPPE
  • Publication number: 20160046703
    Abstract: The present invention relates to a novel antigen-binding protein construct or “modubody”, which contains at least three functional single domain modules of an antibody. The modubodies contain a domain from the heavy chain variable region of an antibody (VH), a domain from the light chain variable region of an antibody (VL) and bind monospecifically to an antigen. The modubodies further contain a domain from the constant region of antibodies. The modubodies can be used for diagnostic or therapeutic purposes.
    Type: Application
    Filed: September 9, 2015
    Publication date: February 18, 2016
    Applicant: ORGENTEC DIAGNOSTIKA GmbH
    Inventor: Robert POPPE
  • Publication number: 20160047825
    Abstract: The present invention relates to a method for releasing bound vitamin D by bringing a sample containing vitamin D into contact with a release reagent which contains at least one hydrotropic substance and at least one transition metal salt. The released vitamin D can subsequently be determined quantitatively. The present invention relates further to a reagent for releasing and optionally determining vitamin D, containing at least one hydrotropic substance and at least one transition metal salt, as well as to the use of such a release reagent for releasing and optionally determining vitamin D.
    Type: Application
    Filed: March 19, 2014
    Publication date: February 18, 2016
    Applicant: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Robert POPPE, Vukic SOSKIC
  • Patent number: 9163079
    Abstract: The present invention relates to a novel antigen-binding protein construct or “modubody”, which contains at least three functional single domain modules of an antibody. The modubodies contain a domain from the heavy chain variable region of an antibody (VH), a domain from the light chain variable region of an antibody (VL) and bind monospecifically to an antigen. The modubodies further contain a domain from the constant region of antibodies. The modubodies can be used for diagnostic or therapeutic purposes.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: October 20, 2015
    Assignee: Orgentec Diagnostika GmbH
    Inventor: Robert Poppe
  • Publication number: 20150241422
    Abstract: The invention relates to methods, reagents and devices for detecting an analyte in a sample.
    Type: Application
    Filed: October 9, 2013
    Publication date: August 27, 2015
    Applicant: ORGENTEC DIAGNOSTIKA GMBH
    Inventors: Vinzenz Kirste, Wigbert Berg, Vukic Soskic
  • Publication number: 20120276099
    Abstract: The present invention relates to a novel antigen-binding protein construct or “modubody”, which contains at least three functional single domain modules of an antibody. The modubodies contain a domain from the heavy chain variable region of an antibody (VH), a domain from the light chain variable region of an antibody (VL) and bind monospecifically to an antigen. The modubodies further contain a domain from the constant region of antibodies. The modubodies can be used for diagnostic or therapeutic purposes.
    Type: Application
    Filed: November 24, 2010
    Publication date: November 1, 2012
    Applicant: ORGENTEC DIAGNOSTIKA GMBH
    Inventor: Robert Poppe