Patents Assigned to ORGENTEC DIAGNOSTIKA GMBH
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Patent number: 11199553Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.Type: GrantFiled: October 4, 2018Date of Patent: December 14, 2021Assignee: ORGENTEC DIAGNOSTIKA GMBHInventors: Vukic Soskic, Robert Poppe
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Patent number: 10571464Abstract: The invention relates to methods, reagents and devices for detecting an analyte in a sample.Type: GrantFiled: October 9, 2013Date of Patent: February 25, 2020Assignee: Orgentec Diagnostika GmbHInventors: Vinzenz Kirste, Wigbert Berg, Vukic Soskic
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Publication number: 20190101548Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.Type: ApplicationFiled: October 4, 2018Publication date: April 4, 2019Applicant: ORGENTEC DIAGNOSTIKA GMBHInventors: Vukic SOSKIC, Robert POPPE
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Patent number: 10222388Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.Type: GrantFiled: August 1, 2014Date of Patent: March 5, 2019Assignee: ORGENTEC DIAGNOSTIKA GMBHInventors: Vukic Soskic, Robert Poppe
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Patent number: 9863963Abstract: The present invention relates to a method for releasing bound vitamin D by bringing a sample containing vitamin D into contact with a release reagent which contains at least one hydrotropic substance and at least one transition metal salt. The released vitamin D can subsequently be determined quantitatively. The present invention relates further to a reagent for releasing and optionally determining vitamin D, containing at least one hydrotropic substance and at least one transition metal salt, as well as to the use of such a release reagent for releasing and optionally determining vitamin D.Type: GrantFiled: March 19, 2014Date of Patent: January 9, 2018Assignee: ORGENTEC DIAGNOSTIKA GMBHInventors: Robert Poppe, Vukic Soskic
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Publication number: 20170115313Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.Type: ApplicationFiled: August 1, 2014Publication date: April 27, 2017Applicant: ORGENTEC DIAGNOSTIKA GMBHInventors: Vukic SOSKIC, Robert POPPE
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Publication number: 20160195556Abstract: The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for producing these vitamin D compounds and to the use of an intermediate for producing these compounds. The present invention also relates to a method for quantitatively determining vitamin D using a vitamin D compound according to the invention as a tracer. Furthermore, the present invention relates to a reagent for determining vitamin D, containing a compound according to the invention, and to the use thereof for determining vitamin D.Type: ApplicationFiled: August 1, 2014Publication date: July 7, 2016Applicant: ORGENTEC DIAGNOSTIKA GMBHInventors: Vukic SOSKIC, Robert POPPE
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Publication number: 20160047825Abstract: The present invention relates to a method for releasing bound vitamin D by bringing a sample containing vitamin D into contact with a release reagent which contains at least one hydrotropic substance and at least one transition metal salt. The released vitamin D can subsequently be determined quantitatively. The present invention relates further to a reagent for releasing and optionally determining vitamin D, containing at least one hydrotropic substance and at least one transition metal salt, as well as to the use of such a release reagent for releasing and optionally determining vitamin D.Type: ApplicationFiled: March 19, 2014Publication date: February 18, 2016Applicant: ORGENTEC DIAGNOSTIKA GMBHInventors: Robert POPPE, Vukic SOSKIC
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Publication number: 20160046703Abstract: The present invention relates to a novel antigen-binding protein construct or “modubody”, which contains at least three functional single domain modules of an antibody. The modubodies contain a domain from the heavy chain variable region of an antibody (VH), a domain from the light chain variable region of an antibody (VL) and bind monospecifically to an antigen. The modubodies further contain a domain from the constant region of antibodies. The modubodies can be used for diagnostic or therapeutic purposes.Type: ApplicationFiled: September 9, 2015Publication date: February 18, 2016Applicant: ORGENTEC DIAGNOSTIKA GmbHInventor: Robert POPPE
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Patent number: 9163079Abstract: The present invention relates to a novel antigen-binding protein construct or “modubody”, which contains at least three functional single domain modules of an antibody. The modubodies contain a domain from the heavy chain variable region of an antibody (VH), a domain from the light chain variable region of an antibody (VL) and bind monospecifically to an antigen. The modubodies further contain a domain from the constant region of antibodies. The modubodies can be used for diagnostic or therapeutic purposes.Type: GrantFiled: November 24, 2010Date of Patent: October 20, 2015Assignee: Orgentec Diagnostika GmbHInventor: Robert Poppe
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Publication number: 20150241422Abstract: The invention relates to methods, reagents and devices for detecting an analyte in a sample.Type: ApplicationFiled: October 9, 2013Publication date: August 27, 2015Applicant: ORGENTEC DIAGNOSTIKA GMBHInventors: Vinzenz Kirste, Wigbert Berg, Vukic Soskic
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Publication number: 20120276099Abstract: The present invention relates to a novel antigen-binding protein construct or “modubody”, which contains at least three functional single domain modules of an antibody. The modubodies contain a domain from the heavy chain variable region of an antibody (VH), a domain from the light chain variable region of an antibody (VL) and bind monospecifically to an antigen. The modubodies further contain a domain from the constant region of antibodies. The modubodies can be used for diagnostic or therapeutic purposes.Type: ApplicationFiled: November 24, 2010Publication date: November 1, 2012Applicant: ORGENTEC DIAGNOSTIKA GMBHInventor: Robert Poppe