Patents Assigned to Orion Therapeutic Systems, Inc.
  • Fibrinolysis and fibrinogenolysis treatment
    Patent number: 5407673
    Abstract: Disclosed is a fibrinolysis and fibrinogenolysis treatment which includes parenterally introducing into the body of a human patient human plasmin in fibrinolytically and fibrinogenolytically active form at a concentration and for a time sufficient to permit fibrinolytically and fibrinogenolytically active human plasmin to reach a concentration about the site of any intravascular clot sufficient to lyse the clot and/or to reduce circulating fibrinogen levels.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: April 18, 1995
    Assignee: Orion Therapeutic Systems, Inc.
    Inventors: Edward Reich, Thomas G. Easton
  • Injection/activation apparatus
    Patent number: 5378232
    Abstract: Disclosed is apparatus for administration of a drug in active form, which includes means defining a prodrug reaction zone including an immobilized enzyme for modifying chemically a prodrug to a physiologically compatible, physiologically active drug form, means in communication with the reaction zone for establishing parenteral access to the body of a patient, and means for transporting a prodrug through the reaction zone at a rate sufficient to convert the prodrug to the active drug form and then into the body of a patient.
    Type: Grant
    Filed: August 28, 1991
    Date of Patent: January 3, 1995
    Assignee: Orion Therapeutic Systems, Inc.
    Inventors: Thomas G. Easton, Edward Reich
  • Fibrinolysis and fibrinogenolysis treatment
    Patent number: 5288489
    Abstract: Disclosed is a fibrinolysis and fibrinogenolysis treatment which includes parenterally introducing into the body of a human patient human plasmin in fibrinolytically and fibrinogenolytically active form at a concentration and for a time sufficient to permit fibrinolytically and fibrinogenolytically active human plasmin to reach a concentration about the site of an intravascular clot sufficient to lyse the clot and/or to reduce circulating fibrinogen levels.
    Type: Grant
    Filed: August 28, 1991
    Date of Patent: February 22, 1994
    Assignee: Orion Therapeutic Systems, Inc.
    Inventors: Edward Reich, Thomas G. Easton