Abstract: A method for assessing tissue remodeling risk is provided. The method comprises (a) obtaining a plurality of images of a target region of a subject's skin, wherein the plurality of images comprises (1) a set of visible light images and (2) a set of fluorescent images; (b) processing the plurality of images to determine an optimal image pair for the target region, wherein the optimal image pair comprises: (i) a first visible light image selected from (1), and (ii) a first fluorescent image selected from (2); (c) generating an assessment of the target region based at least on the optimal image pair; and (d) displaying on a graphical user interface the assessment, the optimal image pair, and a schematic showing a location of the target region on the subject's body, wherein the assessment is indicative of a probability of tissue remodeling at the target region.

Abstract: The present invention relates to a device and a method. The device of the present invention comprising a patch comprising: a substrate, and an adhesive on the substrate. Further, the patch is configured to be attached to a skin via the adhesive to form a pocket between the patch and the skin, to allow introduction of a material into the pocket, and to hold the material within the pocket.

Abstract: Methods, compositions and systems are provided for the imaging of cavity/tissue lesions, including without limitation cavity/tissue malignant lesions, e.g. cancers of the skin, mouth, colon, digestive system cervix, bladder, lung, etc.

Abstract: Methods, compositions and systems are provided for the imaging of cavity/tissue lesions, including without limitation cavity/tissue malignant lesions, e.g. cancers of the skin, mouth, colon, digestive system cervix, bladder, lung, etc.

Abstract: Methods and compositions are provided for the analysis of skin surfaces to determine the presence of neoplastic tissue. In the methods of the invention, a composition comprising a florescent probe that binds to a specific neoplasia associated marker is applied topically to the area of interest. After topical administration, the probe preferentially binds to markers associated in neoplastic lesions in situ, which binding is detected with a compact illumination unit that provides illumination at a wavelength appropriate for image acquisition. The illumination unit comprises a light source and fiber optic bundle to direct the light towards the area of examination. A detection unit is used to capture and record an image of the area of investigation. The detection unit may be a digital camera, film camera, etc. A mapping module may also be provided to catalogue the site of examination.

Abstract: Methods, compositions and systems are provided for the imaging of cavity/tissue lesions, including without limitation cavity/tissue malignant lesions, e.g. cancers of the skin, mouth, colon, digestive system cervix, bladder, lung, etc.