Patents Assigned to Orpegen Medizinische-Molekular Biologische Forschungsgesellschaft mbh
  • Patent number: 5324786
    Abstract: The invention provides a method for the production of a solid phase system of the formula F--(--R.sup.3 --Y--CO--CR.sup.2 .dbd.CR.sup.1 --CH.sub.2 --X).sub.m using new allyl esters of the formula:X--CH.sub.2 --CR.sup.1 .dbd.CR.sup.2 --CO--Y--R.sup.3 --A (I).R.sup.1 and R.sup.2 are hydrogen, halogen, alkyl or aryl, R.sup.3 is a spacer, X is acyloxy where acyl is the residue of an aliphatic carboxylic acid or is RCO-- in which R is an organic group. Y is oxygen or sulphur or an --NH-- group and A is a grouping which can react with a solid carrier material F, which contains functional groups B. A and B are groups which react with one another with condensation and/or addition and formation of a linkage between the solid carrier material and X--CH.sub.2 --CR.sup.1 .dbd.CR.sup.2 --CO--Y--R.sup.3 --.
    Type: Grant
    Filed: May 3, 1991
    Date of Patent: June 28, 1994
    Assignee: Orpegen Medizinische-Molekular Biologische Forschungsgesellschaft mbh
    Inventors: Horst Kunz, Winfried Kosch, Joachim Marz