Patents Assigned to Orpegen Pharma GmbH
  • Basophil degranulation test
    Patent number: 6835551
    Abstract: The present invention concerns a method for determining the degranulation activity of basophilic granulocytes in a sample as well as a reagent kit that is suitable for this. Furthermore the invention also concerns a method for diagnosing allergic hypersensitivity and for monitoring the response to a hyposensitization therapy.
    Type: Grant
    Filed: February 10, 1999
    Date of Patent: December 28, 2004
    Assignee: Orpegen Pharma GmbH
    Inventors: Carl Thomas Nebe, Hartmann Karin
  • Test system for determining the activity of natural killer cells
    Patent number: 5902733
    Abstract: The invention concerns a method for determining the action of effectors on target cells, wherein thawed cryopreserved mammalian cells are used without prior culture as target cells which have a vitality of at least 85% after storage at -70.degree. C. for a period of 4 weeks and are obtainable by preparing a suspension of the target cells in a medium, adding a cryopreservative up to a final concentration of 2-10% (v/v) and freezing the cells with a temperature decrease of no more than 2.degree. C. per minute.
    Type: Grant
    Filed: February 17, 1998
    Date of Patent: May 11, 1999
    Assignee: Orpegen Pharma GmbH
    Inventors: Werner Hirt, Volker Ehemann, Alexander Wink