Abstract: A PAT nonapeptide of formula EAKSQGGSD (SEQ ID NO: 1) can be used to treat or prevent neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis. Pharmaceutical compositions containing the PAT nonapeptide can be formulated for administration by parenteral route, including the subcutaneous, intraperitoneal, intravenous or intranasal routes.
Type:
Grant
Filed:
November 2, 2015
Date of Patent:
October 18, 2016
Assignee:
ORPHIT
Inventors:
Claude Laruelle, Jamal Temsamani, Frederic Mourlane