Patents Assigned to OrPro Therapeutics, Inc.
  • THIOL-BASED MULTIVALENT DRUG DELIVERY COMPOSITIONS
    Publication number: 20240358844
    Abstract: The present invention is related to a drug delivery composition that includes a thioredoxin homologue protein having an N-terminal monocysteinic active site, with the cysteine residue of the active site in a reduced state and an active agent conjugated to the thioredoxin homologue protein and methods of making and using the composition.
    Type: Application
    Filed: June 4, 2024
    Publication date: October 31, 2024
    Applicant: ORPRO THERAPEUTICS, INC.
    Inventors: Peter B. HEIFETZ, Haim MOSKOWITZ
  • Product and process for mucus viscosity normalization
    Patent number: 9168290
    Abstract: Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The composition contains a protein or peptide containing a thioredoxin monocysteinic active site in a reduced state and optionally further contains a reducing system.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: October 27, 2015
    Assignee: OrPro Therapeutics, Inc.
    Inventor: Peter B. Heifetz
  • PRODUCT AND PROCESS FOR MUCUS VISCOSITY NORMALIZATION
    Publication number: 20140271599
    Abstract: Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The composition contains a protein or peptide containing a thioredoxin monocysteinic active site in a reduced state and optionally further contains a reducing system.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Applicant: OrPro Therapeutics, Inc.
    Inventor: Peter B. Heifetz