Patents Assigned to OrsoBio, Inc.
  • LXR modulators with bicyclic core moiety
    Patent number: 12291523
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXRa and/or LXKJ3) and act preferably as inverse agonists of LXR.
    Type: Grant
    Filed: March 5, 2024
    Date of Patent: May 6, 2025
    Assignee: ORSOBIO, INC.
    Inventors: Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle
  • Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives
    Patent number: 12049439
    Abstract: Provided is a compound of Formula (I): wherein the variable groups are defined herein.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: July 30, 2024
    Assignee: OrsoBio, Inc.
    Inventors: Julie Farand, Joshua A. Kaplan, Gregory Notte, Casey Lockwood Olen, Michael Sangi, David Sperandio
  • LXR modulators with bicyclic core moiety
    Patent number: 11970484
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
    Type: Grant
    Filed: February 9, 2023
    Date of Patent: April 30, 2024
    Assignee: OrsoBio, Inc.
    Inventors: Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle
  • Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors
    Patent number: 11780812
    Abstract: The present invention is related to a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of aminocarboxymuconate semialdehyde decarboxylase (ACMSD).
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: October 10, 2023
    Assignee: OrsoBio, Inc.
    Inventors: Taisuke Takahashi, Nan Ji
  • LXR modulators with bicyclic core moiety
    Patent number: 11618747
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: April 4, 2023
    Assignee: OrsoBio, Inc.
    Inventors: Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle