Patents Assigned to ORTH CONSULTING, LLC
  • Patent number: 12070543
    Abstract: A detoxification method for treating sepsis, microbial infections, and other inflammatory conditions includes the steps of inducing flow of patient blood through a blood treatment device consisting of a bioreactor inlet and outlet in fluid connection to the circulatory system of a patient. Biological agents including lipopolysaccharide (LPS) and extracellular adenosine triphosphate (ATP) contained within patient blood can be irreversibly detoxified by passage of patient blood over a bioreactor surface having attached or immobilized alkaline phosphatase enzymes and acyloxyacyl hydrolase enzyme, with the bioreactor being contained within the blood treatment device. The method uses continuous treatment of a patient's blood to convert LPS and extracellular ATP in blood into inhibitors of inflammation in vivo without adding any chemicals to the bloodstream of the patient.
    Type: Grant
    Filed: May 24, 2023
    Date of Patent: August 27, 2024
    Assignee: Orth Consulting, LLC
    Inventors: Donald S. Orth, Roger W. Orth
  • Patent number: 12070541
    Abstract: A blood treatment method includes the steps of inducing flow of a patient's blood through a blood treatment device inlet and outlet in fluid connection to the circulatory system of the patient. Metastatic deoxyribonucleic acid (DNA) contained within patient blood is destroyed by passing a patient's blood over a bioreactor surface having attached or immobilized deoxyribonuclease 1 (DNase 1) enzyme. The blood treatment device which consists of a bioreactor containing immobilized DNase 1, enables continuous treatment of a patient's blood and increases the effective concentration of DNase 1 in a patient's bloodstream to convert metastasizing cancer DNA in blood into non-oncogenic nucleotide fragments in vivo without adding any chemicals to the blood of the patient.
    Type: Grant
    Filed: May 24, 2023
    Date of Patent: August 27, 2024
    Assignee: Orth Consulting, LLC
    Inventors: Donald S. Orth, Roger W. Orth
  • Patent number: 11389581
    Abstract: A blood treatment method includes the steps of inducing flow of a patient's blood through an extracorporeal device inlet and outlet in fluid connection to the circulatory system of the patient. Metastatic DNA contained within patient blood can be rendered non-oncogenic by passing patient blood over a biochemical reactor surface having attached or immobilized DNase 1 enzyme, with the biochemical reactor being contained within the extracorporeal device. The treatment method is performed without adding any chemicals to the blood of the patient.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: July 19, 2022
    Assignee: ORTH CONSULTING, LLC
    Inventor: Donald S. Orth
  • Patent number: 11305045
    Abstract: A detoxification method includes the steps of inducing flow of patient blood through an extracorporeal device inlet and outlet in fluid connection to the circulatory system of a patient. Biological agents including lipopolysaccharide (LPS) contained within patient blood can be detoxified by passing patient blood over a biochemical reactor surface having attached or immobilized Saccharomyces boulardii alkaline phosphatase enzyme, with the biochemical reactor being contained within the extracorporeal device. An acyloxyacyl hydrolase enzyme may also be used on the biochemical reactor surface.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: April 19, 2022
    Assignee: ORTH CONSULTING, LLC
    Inventor: Donald S. Orth
  • Patent number: 11208178
    Abstract: Manually propelled water skis support a person skiing on water. The water ski includes a base having a binding on an upper surface and stationary propulsion structures with uniform height on the bottom surface. The propulsion structures include a rearward facing and vertical propulsion surface and a forward facing and sloped surface such that drag is greater when the water ski is moved rearwardly. The propulsion surface may be arcuate, V-shape, U-shaped, or other shaped in a horizontal plane and may also be circularly concave in a vertical plane. Buoyancy structures may be secured to the upper surface of the base forward and rearward of the binding. Water ski poles including elliptically- or cylindrically-shaped floats at the bottom ends may be used to provide a synergistic increase in waterskiing speed. Straps on the base near the binding may be used to secure the water ski poles to the base in order to form an outrigger.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: December 28, 2021
    Assignee: ORTH CONSULTING, LLC
    Inventor: Donald S. Orth
  • Patent number: 11103628
    Abstract: A detoxification method includes the steps of inducing flow of patient blood through an extracorporeal device inlet and outlet in fluid connection to the circulatory system of a patient. Biological agents including lipopolysaccharide (LPS) contained within patient blood can be detoxified by passing patient blood over a biochemical reactor surface having attached or immobilized Saccharomyces boulardii alkaline phosphatase enzyme, with the biochemical reactor being contained within the extracorporeal device.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: August 31, 2021
    Assignee: ORTH CONSULTING, LLC
    Inventor: Donald S. Orth
  • Patent number: 10926849
    Abstract: Manually propelled water skis support a person skiing on water. The water ski includes a base having a binding on an upper surface and propulsion structures on the bottom surface. The propulsion structures include a rearward facing and vertical propulsion surface and a forward facing and sloped surface such that drag is greater when the water ski is moved rearwardly. The propulsion surface may be arcuate, V-shape, U-shaped, or other shaped in a horizontal plane and may also be concave in a vertical plane. Buoyancy structures may be secured to the upper surface of the base forward and rearward of the binding. Water ski poles including elliptical floats at the bottom ends may be used to provide a synergistic increase in waterskiing speed. Straps on the base near the binding may be used to secure the water ski poles to the base in order to form an outrigger.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: February 23, 2021
    Assignee: ORTH CONSULTING, LLC
    Inventor: Donald S. Orth
  • Patent number: 10881781
    Abstract: A detoxification method includes the steps of inducing flow of patient blood through an extracorporeal device inlet and outlet in fluid connection to the circulatory system of a patient. Biological agents including lipopolysaccharide (LPS) contained within patient blood can be detoxified by passing patient blood over a biochemical reactor surface having attached or immobilized Saccharomyces boulardii alkaline phosphatase enzyme, with the biochemical reactor being contained within the extracorporeal device.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: January 5, 2021
    Assignee: ORTH CONSULTING, LLC
    Inventor: Donald S. Orth