Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
November 25, 2002
Date of Patent:
March 23, 2004
Ortho-McNeil Pharamceutical, Inc.
Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
Abstract: Bicyclic heterocyclic substituted phenyl oxazolidinone compounds of the formula:
wherein Y is a radical of the formulae II or III:
in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
Abstract: This invention provides folic acid-containing pharmaceutical compositions comprising either an oral contraceptive or a hormone replacement composition. This invention also provides methods of administering folic acid to a subject using the instant pharmaceutical compositions. Finally, this invention provides a drug delivery system useful for administering the instant pharmaceutical compositions.