Patents Assigned to Ortho Pharmaceutical
  • Mutant human T cell line producing immunosuppressive factor and method for obtaining such mutants
    Patent number: 4728614
    Abstract: A stable mutant human T cell line is disclosed which secretes a high titer suppressor inducer factor. This suppressor inducer factor in turn induces production of a T cell suppressor factor which suppressed mitogen-induced T cell proliferation at high dilution. Also disclosed is a general method for mutating lymphoblastoid cell lines to yield mutants secreting enhanced levels of lymphokines.
    Type: Grant
    Filed: March 5, 1984
    Date of Patent: March 1, 1988
    Assignee: Ortho Pharmaceutical
    Inventor: Catherine Y. Lau
  • Peptic ulcer treatment method
    Patent number: 4707495
    Abstract: A method of treating peptic ulcer disease by topical application of a prostaglandin analog is described.
    Type: Grant
    Filed: October 28, 1985
    Date of Patent: November 17, 1987
    Assignee: Ortho Pharmaceutical
    Inventors: Marvin E. Rosenthale, David A. Shriver, Laurence B. Katz
  • Monoclonal antibody to human T cells
    Patent number: 4680383
    Abstract: Hybrid cell line for producing of monoclonal antibody to an antigen found on all normal human T cells. The hybrid is formed by fusing splenocytes from immunized Balb/cJ mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: July 14, 1987
    Assignee: Ortho Pharmaceutical
    Inventors: Patrick C. Kung, Gideon Goldstein