Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
Type:
Grant
Filed:
August 10, 2001
Date of Patent:
October 21, 2003
Assignee:
Ortho-Pharmaceutical, Inc.
Inventors:
Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei