Abstract: The present application relates to a lyophilized scaffold composition having at least one polysaccharide wherein said scaffold is substantially solid and capable of being formed into a desired shape; wherein the at least one polysaccharide has a protonation level resulting in controlled rehydration of said scaffold, such that when said scaffold is contacted with at least one of a neutral aqueous solution, blood, blood derived fluid and combinations thereof, said scaffold forms a microparticle dispersion and stimulates tissue remodeling and anabolic wound repair, a process for preparing a lyophilized scaffold composition and the use of a lyophilized scaffold composition for wound repair in a mammal.
Type:
Grant
Filed:
February 20, 2015
Date of Patent:
December 19, 2023
Assignee:
ORTHO REGENERATIVE TECHNOLOGIES INC.
Inventors:
Caroline Hoemann, Daniel Veilleux, Michael D. Buschmann
Abstract: The present application relates to a freeze-dried polymer composition containing chitosan and at least one lyoprotectant, a process for preparing a freeze-dried composition containing chitosan and at least one lyoprotectant and the use of a reconstituted freeze-dried chitosan composition to prepare implants for tissue repair.
Type:
Grant
Filed:
February 20, 2015
Date of Patent:
March 29, 2022
Assignee:
Ortho Regenerative Technologies Inc.
Inventors:
Anik Chevrier, Michael D. Buschmann, Daniel Veilleux, Caroline Hoemann, Marc Lavertu
Abstract: The present description relates to a polymer composition for use in repairing tissue of a patient comprising at least one blood component, as polymer, such a chitosan, and at least one inorganic salt, such as NaCl, method of the composition and method of preparing the composition.
Type:
Application
Filed:
June 22, 2017
Publication date:
November 23, 2017
Applicant:
ORTHO REGENERATIVE TECHNOLOGIES INC.
Inventors:
Wei Ouyang, Michael Buschmann, Caroline Hoemann, Marc Lavertu, Anik Chevrier
Abstract: The present application relates to a lyophilized scaffold composition having at least one polysaccharide wherein said scaffold is substantially solid and capable of being formed into a desired shape; wherein the at least one polysaccharide has a protonation level resulting in controlled rehydration of said scaffold, such that when said scaffold is contacted with at least one of a neutral aqueous solution, blood, blood derived fluid and combinations thereof, said scaffold forms a microparticle dispersion and stimulates tissue remodeling and anabolic wound repair, a process for preparing a lyophilized scaffold composition and the use of a lyophilized scaffold composition for wound repair in a mammal.
Type:
Application
Filed:
February 20, 2015
Publication date:
March 2, 2017
Applicant:
ORTHO REGENERATIVE TECHNOLOGIES INC.
Inventors:
Caroline Hoemann, Daniel Veilleux, Michael D. Buschmann
Abstract: The present application relates to a freeze-dried polymer composition containing chitosan and at least one lyoprotectant, a process for preparing a freeze-dried composition containing chitosan and at least one lyoprotectant and the use of a reconstituted freeze-dried chitosan composition to prepare implants for tissue repair.
Type:
Application
Filed:
February 20, 2015
Publication date:
February 23, 2017
Applicant:
ORTHO REGENERATIVE TECHNOLOGIES INC.
Inventors:
Anik Chevrier, Michael D. Buschmann, Daniel Veilleux, Caroline Hoemann, Marc Lavertu
Abstract: The present disclosure relates to an activated polymer composition for use in repairing tissue of a patient comprising platelet-rich plasma (PRP), a chitosan solution, a salt such as NaCI or glycerol phosphate, and an activator such as at least one of CaCI2 and a mixture of thrombin/CaCI2.
Type:
Grant
Filed:
November 19, 2010
Date of Patent:
August 30, 2016
Assignee:
ORTHO REGENERATIVE TECHNOLOGIES INC.
Inventors:
Wei Ouyang, Michael Buschmann, Anik Chevrier