• Patent number: 10624995
    Abstract: Disclosed are novel compositions and methods for making a polymer substrate and a ligand that includes a proximal portion with a photoactive compound bound to the polymer substrate, a terminal portion with an anti-infective/anti-microbial compound, and a reactive portion attaching the proximal portion and the terminal portion.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: April 21, 2020
    Assignee: Orthobond Corporation
    Inventors: Randy Clevenger, Se-Ho Kim, Jordan Katz, Carlos Caicedo-Carvajal
  • Patent number: 10596304
    Abstract: Devices are provided which are functionalized to include surface regions having anti-infective agents. Methods are provided for functionalizing various material surfaces to include active surface regions for binding anti-infective agents. Methods are provided by which anti-infective moieties or agents are bonded to functionalized surfaces.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: March 24, 2020
    Assignees: Orthobond Corporation, The Trustees of Princeton University
    Inventors: Randell Clevenger, Thomas J. Dennes, Jeffrey Schwartz
  • Patent number: 10471177
    Abstract: Disclosed in certain embodiments is a composition comprising a biological material and transition metal atoms selected from the group consisting of Group IVB, Group VB, Group VIB of the Periodic Chart and a combination thereof, bound to a surface of the biological material.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: November 12, 2019
    Assignee: Orthobond Corporation
    Inventors: Randell Clevenger, Rong Dong, Jordan Katz
  • Patent number: 10449750
    Abstract: Disclosed in certain embodiments is a composition comprising a first material; an adhesive material attached to the first material; a plurality of linker molecules bonded to the adhesive material; and a second material bonded to the linker molecules.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: October 22, 2019
    Assignee: Orthobond Corporation
    Inventors: Carlos Caicedo-Carvajal, Randy Clevenger, Sam Hong, Jordan Katz, Cheoljin Kim
  • Patent number: 10390533
    Abstract: Articles having metal, metalloid or non-metal surfaces containing an antimicrobial layer comprising antimicrobial oligomers or polymers are suitable for use in medical devices, sanitary surfaces and other applications. Antimicrobial layers contain an organophosphorus layer deposited on an article surface and antimicrobial oligomers or polymers bonded to the organophosphorus layer.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: August 27, 2019
    Inventor: Randell Clevenger