Patents Assigned to Orthogene LLC
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Publication number: 20070149441
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Application
    Filed: February 13, 2007
    Publication date: June 28, 2007
    Applicant: Orthogene LLC
    Inventors: Daniel Aeschlimann, Paul Bulpitt
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Patent number: 7196180
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: March 27, 2007
    Assignee: Orthogene LLC
    Inventors: Daniel Aeschlimann, Paul Bulpitt
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Patent number: 6630457
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: October 7, 2003
    Assignee: Orthogene LLC
    Inventors: Daniel Aeschlimann, Paul Bulpitt