Abstract: The present invention relates to a composition comprising Notoginseng radix extract for preventing and treating arthritis as an effective ingredient. Notoginseng radix extract of the present invention inhibits release of tumor necrosis factor-alpha (TNF-?) and is the death of activated T-cells only, so that it can be effectively used for the production of a medicine for preventing and treating arthritis and health food as well.
Type:
Grant
Filed:
May 9, 2008
Date of Patent:
September 29, 2009
Assignee:
Oscotec Inc.
Inventors:
Jung-Keun Kim, Se-Won Kim, Hyung-Gun Kim, Seon-Yle Ko, Jong-Yeo Kim, Sunhwa Chang, Dong-Heon Baek, Byung-Eui Lee, Seong-Hee Ko, Youngnim Choi, Dong Sik Jung, Heejong Woo
Abstract: The present invention relates to inorganic bone graft materials and a method for preparing the bone graft materials. Particularly, the present invention relates to a method for preparing bone graft materials comprises the following steps: collecting cancellous bones from an animal; removing lipids and organic materials from the cancellous bones using organic solvent, sodium hypochlorite and hydrogen peroxide; and sterilizing the cancellous bones wherefrom the lipids and the organic materials are removed. The bone graft materials prepared by the method of the present invention meet requirements for use in bone grafting, including biocompatibility, sterilization, osteoinductivity and osteoconductivity with free from immunogenecity and toxicity to tissue and are suitable for use in osteogenesis and have morphogenesis.
Type:
Grant
Filed:
September 15, 2005
Date of Patent:
March 24, 2009
Assignee:
Oscotec, Inc.
Inventors:
Chang Joon Yim, Se Won Kim, Jung Keun Kim, Jong Yeo Kim, Hyung Gun Kim, Dong Ryung Shin, Yong Mok Yu, Sung Bin Yim, Seon Yle Ko, Sung Churl Lee
Abstract: The present invention relates to a use of a specific alpha-arylmethoxyacrylate derivative, or its pharmacologically acceptable salt or solvate for preventing and treating metabolic bone diseases.
Type:
Application
Filed:
June 22, 2005
Publication date:
November 13, 2008
Applicants:
Korea Research Institute of Chemical Technology, Oscotec Inc.
Inventors:
Bum Tae Kim, Yong Ki Min, Yeon Soo Lee, Jung Nyoung Heo, Hyuk Lee, No Kyun Park, Jung-Keun Kim, Se-Won Kim, Seon-Yle Ko
Abstract: The present invention relates to inorganic bone graft materials and a method for preparing the bone graft materials. Particularly, the present invention relates to a method for preparing bone graft materials comprises the following steps: collecting cancellous bones from an animal; removing lipids and organic materials from the cancellous bones using organic solvent, sodium hypochlorite and hydrogen peroxide; and sterilizing the cancellous bones wherefrom the lipids and the organic materials are removed. The bone graft materials prepared by the method of the present invention meet requirements for use in bone grafting, including biocompatibility, sterilization, osteoinductivity and osteoconductivity with free from immunogenecity and toxicity to tissue and are suitable for use in osteogenesis and have morphogenesis.
Type:
Application
Filed:
September 15, 2005
Publication date:
January 19, 2006
Applicant:
OSCOTEC, INC.
Inventors:
Chang Joon YIM, Se Won KIM, Jung Keun KIM, Jong Yeo KIM, Hyung Gun KIM, Dong Ryung SHIN, Yung Mok YU, Sung Bin YIM, Seon Yle KO, Sung Churl LEE
Abstract: The present invention relates to a method for preparation of the supersaturated calcium and phosphate ions solution and a method for preparation of the thin film of calcium phosphate crystal on solid surface by using the said solution. Particularly, the lowered temperature and/or the use of suitable buffer system inhibit the nucleation of calcium phosphate in aqueous solution, and thereby highly supersaturated calcium and phosphate ions solution can be prepared. And the thin film of calcium phosphate crystal on solid surface can be prepared with rapidity and good quality of high reactivity and low crystallinity by using the said solution. Also the thin film of calcium phosphate crystal prepared according to the present invention has biocompatibility and can be applied as biomaterials.
Type:
Grant
Filed:
March 2, 2001
Date of Patent:
April 13, 2004
Assignees:
Oscotec Inc.
Inventors:
Hyun-Man Kim, Jea-Seung Ko, Yoon-Ji Kim, Soo-Jin Park