Abstract: Disclosed herein is a method for detecting a binding event between an immobilised primary antibody and a target analyte-secondary antibody-enzyme complex using an electrochemical measurement technique.

Abstract: The present disclosure relates to an actuator, an actuator assembly, a method of operating an actuator, a computer program and a system. In one aspect, an actuator may comprise a plurality of independently operable actuation elements and an operator having an operator surface. Each actuation element may have an actuation surface. The operator may be driveable to move the operator surface along a path to selectively engage with the respective actuation surface of each actuation element to actuate the actuation element.

Abstract: A microfluidic device is provided for conducting multiplex immunoassays to detect multiple target analytes in a liquid sample using a set of tags and anti-tags. The device comprises an array of different anti-tags immobilised on a surface of a sensor for measuring a signal. Each anti-tag is arranged to immobilise a tagged antibody or tagged antigen thereby in use separating tagged immune complexes from the liquid phase affecting the signal measured. The device comprises a sensor chamber for tagged immune complexes to form in the liquid phase and one or more detection zones each comprising the array of different anti-tags for immobilising tagged immune complexes. In use, liquid comprising the tagged immune complexes flows or is fluidically driven from the sensor chamber to the detection zone(s).

Abstract: A device, liquid handling cartridge and related method for detecting the presence or absence of a chemical or biological target within a sample. The method includes the steps of: providing an electrochemical cell with a first electrode module and a second electrode; providing an electronic component between the first electrode module and the second electrode; introducing the sample into the electrochemical cell; measuring the potential difference between the first electrode module and second electrode; and confirming the presence of the chemical or biological target if the measured potential difference exceeds a predetermined threshold value.