Abstract: In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease, diabetes, bone loss, and cancer, using a compound of Formula I.
Type:
Grant
Filed:
August 13, 2019
Date of Patent:
February 20, 2024
Assignee:
OSSIFI THERAPEUTICS LLC
Inventors:
Debra Ellies, F. Scott Kimball, Robert N. Young