Patents Assigned to Ostuka Pharmaceutical Co. Ltd.
  • Low hygroscopic aripiprazole drug substance and processes for the preparation
    Patent number: 8901130
    Abstract: The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous Aripiprazole crystals is stored for an extended period.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: December 2, 2014
    Assignee: Ostuka Pharmaceutical Co., Ltd.
    Inventors: Takuji Bando, Satoshi Aoki, Junichi Kawasaki, Makoto Ishigami, Youichi Taniguchi, Tsuyoshi Yabuuchi, Kiyoshi Fujimoto, Yoshihiro Nishioka, Noriyuki Kobayashi, Tsutomu Fujimura, Masanori Takahashi, Kaoru Abe, Tomonori Nakagawa, Koichi Shinhama, Naoto Utsumi, Michiaki Tominaga, Yoshihiro Ooi, Shohei Yamada, Kenji Tomikawa
  • Method of purification of transforming growth factor-beta
    Patent number: 5047510
    Abstract: The present invention relates to improved methods for purifying TGF-beta so as to obtain such in high yields. The process steps consist of acid-ethanol extracting platelets, cation exchange separation, and hydrophobic separation.
    Type: Grant
    Filed: October 11, 1989
    Date of Patent: September 10, 1991
    Assignee: Ostuka Pharmaceutical Co. Ltd.
    Inventors: James L. Cone, Joseph E. DeLarco