Patents Assigned to OTOLANUM AG
  • Treatment of tinnitus through modulation of chloride co-transporter NKCC1 in the auditory system
    Patent number: 10709682
    Abstract: The present invention relates to the treatment or prevention of tinnitus. More precisely, the present invention relates to a compound modulating chloride co-transporter NKCC1 (chloride co-transporter modulator) for use in the treatment of tinnitus. In addition, the present invention concerns pharmaceutical compositions comprising such an NKCC1 chloride co-transporter modulator as an active agent, a method for the treatment or prevention of tinnitus by administering such a chloride co-transporter modulator, and a screening method for the identification and characterization of compounds capable of modulating chloride co-transporter NKCC1.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: July 14, 2020
    Assignee: Otolanum AG
    Inventors: Marlies Knipper-Breer, Luckas Ruettiger
  • Pharmaceutical composition comprising betahistine
    Patent number: 10456386
    Abstract: The present disclosure relates to a pharmaceutical composition comprising as active substance betahistine or a pharmaceutically acceptable salt thereof, for use in the treatment of otological or neurological disorders in a human subject by intranasal application.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: October 29, 2019
    Assignee: OTOLANUM AG
    Inventors: Christopher John Wraight, Thomas Meyer
  • PHANTOM PHENOMENA TREATMENT
    Publication number: 20150099742
    Abstract: The present invention relates to a substance for the treatment of the phantom phenomena of tinnitus and/or phantom pain, a method for the diagnosis and for the treatment of these phantom phenomena.
    Type: Application
    Filed: December 16, 2014
    Publication date: April 9, 2015
    Applicant: OTOLANUM AG
    Inventors: Marlies KNIPPER-BREER, Lukas Rüttiger
  • TREATMENT OF TINNITUS THROUGH MODULATION OF CHLORIDE CO-TRANSPORTER NKCC1 IN THE AUDITORY SYSTEM
    Publication number: 20150044200
    Abstract: The present invention relates to the treatment or prevention of tinnitus. More precisely, the present invention relates to a compound modulating chloride co-transporter NKCC1 (chloride co-transporter modulator) for use in the treatment of tinnitus. In addition, the present invention concerns pharmaceutical compositions comprising such an NKCC1 chloride co-transporter modulator as an active agent, a method for the treatment or prevention of tinnitus by administering such a chloride co-transporter modulator, and a screening method for the identification and characterization of compounds capable of modulating chloride co-transporter NKCC1.
    Type: Application
    Filed: December 12, 2011
    Publication date: February 12, 2015
    Applicant: OTOLANUM AG
    Inventors: Marlies Knipper, Lukas Ruettiger