Patents Assigned to Otonomy, Inc.
  • Prevention of and Recovery from Drug-Induced Ototoxicity
    Publication number: 20130045957
    Abstract: Provided herein are methods for preventing and/or reducing the severity of drug induced ototoxicity. Provided herein are methods for recovery from hearing loss due to drug-induced ototoxicity.
    Type: Application
    Filed: February 16, 2012
    Publication date: February 21, 2013
    Applicant: Otonomy, Inc.
    Inventors: Fabrice Piu, Qiang Ye, Luis Dellamary, Carl Lebel
  • Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders
    Patent number: 8349353
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with cytotoxic agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: January 8, 2013
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Andrew M. Trammel, Jeffrey P. Harris, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary
  • Controlled release antimicrobial compositions and methods for the treatment of otic disorders
    Patent number: 8318817
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: November 27, 2012
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Jeffrey P. Harris
  • Modulation of Gel Temperature of Poloxamer-Containing Formulations
    Publication number: 20120277199
    Abstract: Disclosed herein are methods for modulation of gel temperature of poloxamer-containing formulations. Also described herein are sustained release pharmaceutical formulations that gel upon contact with the body and are administered by direct application of these compositions and formulations onto or via perfusion into the targeted structure(s).
    Type: Application
    Filed: October 19, 2010
    Publication date: November 1, 2012
    Applicant: Otonomy, Inc.
    Inventors: Qiang Ye, Luis A. Dellamary, Fabrice Piu
  • Controlled-Release CNS Modulating Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20120190671
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: March 20, 2012
    Publication date: July 26, 2012
    Applicants: The Regents of the University of California, Otonomy, Inc.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
  • Controlled release corticosteroid compositions and methods for the treatment of OTIC disorders
    Patent number: 8030297
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: October 4, 2011
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Andrew M. Trammel, Jeffrey P. Harris, Fabrice Piu, Carl Lebel, Qiang Ye, Luis A. Dellamary
  • AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS
    Publication number: 20090306225
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.
    Type: Application
    Filed: April 21, 2009
    Publication date: December 10, 2009
    Applicants: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Andrew M. TRAMMEL, Sergio G. DURON, Fabrice PIU, Luis A. DELLAMARY, Qiang YE, Carl LEBEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS