Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with anti-apoptotic agent or pro-apoptotic agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
July 9, 2009
Publication date:
January 21, 2010
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice PIU, Qiang Ye, Luis A. Dellamary, Michael Christopher Scaife, Andrew M. Trammel, Jeffrey P. Harris
Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with auris sensory cell modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
July 16, 2009
Publication date:
January 21, 2010
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with ion channel modulators. In these methods, the ion channel modulator compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the ion channel modulator compositions and formulations onto the auris interna target areas, or via perfusion into the auris interna structures.
Type:
Application
Filed:
July 21, 2009
Publication date:
January 21, 2010
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
Abstract: Disclosed herein are delivery devices for use in the treatment of otic disorders wherein the delivery device is administered locally to an individual afflicted with an otic disorder, through direct application or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
July 21, 2009
Publication date:
January 21, 2010
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
May 14, 2009
Publication date:
January 14, 2010
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Michael Christopher SCAIFE, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Carl LEBEL, Andrew M. TRAMMEL, Jeffrey P. Harris
Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with aural pressure modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
June 17, 2009
Publication date:
January 7, 2010
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Michael Christopher SCAIFE, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Carl LEBEL, Andrew M. TRAMMEL, Jeffrey P. HARRIS
Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with cytotoxic agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
June 29, 2009
Publication date:
December 31, 2009
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
June 29, 2009
Publication date:
December 31, 2009
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice PIU, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.
Type:
Application
Filed:
April 21, 2009
Publication date:
December 10, 2009
Applicants:
Otonomy, Inc., The Regents of the University of California
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Andrew M. TRAMMEL, Sergio G. DURON, Fabrice PIU, Luis A. DELLAMARY, Qiang YE, Carl LEBEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agent compositions and formulations administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
Type:
Application
Filed:
May 26, 2009
Publication date:
December 3, 2009
Applicants:
OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Michael Christopher SCAIFE, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Carl LEBEL, Jeffrey P. Harris, Andrew M. TRAMMEL