Patents Assigned to Otsuka America Pharmaceutical, Inc.
  • Patent number: 10280141
    Abstract: The present invention relates to crystalline forms of (1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochloride and compositions comprising the same and methods of making and using the same.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: May 7, 2019
    Assignee: OTSUKA AMERICA PHARMACEUTICAL, INC.
    Inventors: Anthony Alexander McKinney, Franklin Bymaster, Walter Piskorski, Fred J. Fleitz, Yonglai Yang, David A. Engers, Valeriya Smolenskaya, Venkat Kusukuntla
  • Patent number: 10039746
    Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: August 7, 2018
    Assignee: OTSUKA AMERICA PHARMACEUTICAL, INC.
    Inventors: Phil Skolnick, Anthony Basile, Zhengming Chen, Joseph W. Epstein
  • Patent number: 9566421
    Abstract: The present invention provides a device, a system, and a method for application of fluids.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: February 14, 2017
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Ronald J. Casey, Patrick P. Vanek, Royal D. Hathaway, David L. Foshee, Theodore J. Mosler, Nicholas J. Jardine, Kristin L. Benokraitis
  • Publication number: 20160063210
    Abstract: Systems and methods for healthcare system administration are described. Data may be acquired through a variety of methods and predictive analytics and indicators may be determined. Tools used may include membership cards with information concerning a consumer of healthcare services and/or an activity monitor for determining levels of activity. A caregiver check-in tool may provide additional data regarding the status of the caregiver and/or the consumer.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Applicant: Otsuka America Pharmaceutical, Inc.
    Inventors: John A. BARDI, Jonathan P. ALFORD, James E. GRAFMYRE, Gillian M. CANNON, John P. DOCHERTY
  • Patent number: 9044733
    Abstract: The invention provides a novel apparatus and method for preparing a solution of a shear sensitive material.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: June 2, 2015
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Royal D. Hathaway, Jr., Joseph R. Sclafani, Jr.
  • Patent number: 9034256
    Abstract: The invention provides a novel apparatus and method for preparing a solution of a shear sensitive material.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: May 19, 2015
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Royal D. Hathaway, Jr., Joseph R. Sclafani, Jr.
  • Patent number: 8911771
    Abstract: The present invention provides a device and a method for application of topical antiseptics. The device comprises a handle; a base coupled to the handle; and a substantially hydrophilic foam coupled to the base. The substantially hydrophilic foam is configured to receive the topical antiseptic.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: December 16, 2014
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Patrick P. Vanek, Henry L. Lewkowicz
  • Patent number: 8858484
    Abstract: The present invention provides a device, a system, and a method for application of fluids.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: October 14, 2014
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Ronald J. Casey, Patrick P. Vanek, Royal D. Hathaway, David L. Foshee, Theodore J. Mosler, Nicholas J. Jardine, Kristin L. Benokraitis
  • Publication number: 20130330114
    Abstract: The present invention provides a device, a system, and a method for application of fluids.
    Type: Application
    Filed: August 13, 2013
    Publication date: December 12, 2013
    Applicant: Otsuka America Pharmaceutical, Inc.
    Inventors: Ronald J. Casey, Patrick P. Vanek, Royal D. Hathaway, David L. Foshee, Theodore J. Mosler, Nicholad J. Jardine, Kristin L. Benokraitis
  • Patent number: 6998469
    Abstract: The present invention comprises a method of purifying GPVI, GPVI peptides, cDNA and protein sequence, and methods for using GPVI and antibodies directed against GPVI.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: February 14, 2006
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Narendra Nath Tandon, Bing Sun, Takashi Nakamura, Naomasa Yamamoto
  • Publication number: 20040152628
    Abstract: The present invention comprises a method of purifying GPVI, GPVI peptides, cDNA and protein sequence, and methods for using GPVI and antibodies directed against GPVI.
    Type: Application
    Filed: May 29, 2003
    Publication date: August 5, 2004
    Applicant: Otsuka America Pharmaceutical Inc.
    Inventors: Narendra Nath Tandon, Bing Sun, Takashi Nakamura, Naomasa Yamamoto
  • Publication number: 20030186885
    Abstract: The present invention comprises a method of purifying GPVI, GPVI peptides, cDNA and protein sequence, and methods for using GPVI and antibodies directed against GPVI.
    Type: Application
    Filed: May 29, 2003
    Publication date: October 2, 2003
    Applicant: Otsuka America Pharmaceutical Inc.
    Inventors: Narendra Nath Tandon, Bing Sun, Takashi Nakamura, Naomasa Yamamoto
  • Patent number: 5877167
    Abstract: A method of inhibiting tumor cell chemotactic motility and/or chemoinvasion, a method of inhibiting phagokinetic activity of tumor cells and neutrophils, a method of inhibiting tumor cell metastasis and a method of inhibiting inflammation due to motility and invasion into blood vessel walls of neutrophils comprising contacting the cells or administering to a host in need of treatment an inhibitory amount of an agent selected from the group consisting of sphingosine-1-phosphate, derivatives of sphingosine-1-phosphate, and mimetics of the sphingosine-1-phosphate or of the derivatives, and pharmaceutically acceptable salts of the agent. A method of preparing sphingosine-1-phosphate and its derivatives is also described.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: March 2, 1999
    Assignee: Otsuka America Pharmaceutical, Inc.
    Inventors: Yasuyuki Igarashi, Fugiang Ruan, Yoshito Sadahira, Shigeyuki Kawa, Sen-itiroh Hakomori