Patents Assigned to Oxford Biomedia (UK) Limited
  • Vector system
    Patent number: 7259015
    Abstract: Provided are retroviral vector genomes and vector systems comprising the genomes. In particular, a retroviral vector genome comprising two or more NOIs, operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and, optionally, Aromatic Amino Acid Dopa Decarboxylase are provided.
    Type: Grant
    Filed: April 7, 2003
    Date of Patent: August 21, 2007
    Assignee: Oxford Biomedia (UK) Limited
    Inventors: Alan John Kingsman, Nicholas D. Mazarakis, Enca Martin-Rendon, Mimoun Azzouz, Jonathan Rohll
  • Lentiviral LTR-deleted vector
    Patent number: 7056699
    Abstract: A vector capable of transducing non-dividing and/or slowly dividing cells is provided, wherein the vector is a lentiviral LTR-deleted vector. Also provided is a method for producing a protein of interest in a non-dividing or slowly dividing cell by transducing the cell with a lentiviral LTR-deleted vector and expressing the protein of interest in the cell. In addition, target cells containing the lentiviral LTR-deleted vector are provided.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: June 6, 2006
    Assignee: Oxford Biomedia (UK) Limited
    Inventors: Alan John Kingsman, Susan Mary Kingsman